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Descriptor English: Bortezomib
Descriptor Spanish: Bortezomib
Descriptor bortezomib
Scope note: Un derivado de las pirazinas y de los ácidos borónicos que actúa como INHIBIDOR DE PROTEASOMA reversible. Se utiliza como un ANTINEOPLÁSICO en el tratamiento del MIELOMA MÚLTIPLE y LINFOMA DE CÉLULAS DEL MANTO.
Descriptor Portuguese: Bortezomib
Descriptor French: Bortézomib
Entry term(s): 341, PS
LDP 341
LDP-341
LDP341
PS 341
PS-341
PS341
Velcade
Tree number(s): D01.029.260.110.500
D01.132.285.500
D02.203.200.500
D03.383.679.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069286
Scope note: A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of MULTIPLE MYELOMA and MANTLE CELL LYMPHOMA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Registry Number: 69G8BD63PP
Public MeSH Note: 2016; BORTEZOMIB was indexed under BORONIC ACIDS and PYRAZINES 2000-2015
History Note: 2016 (2000)
DeCS ID: 55856
Unique ID: D000069286
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/27
Bortezomib - Preferred
Concept UI M0350110
Scope note A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of MULTIPLE MYELOMA and MANTLE CELL LYMPHOMA.
Preferred term Bortezomib
LDP-341 - Narrower
Concept UI M0560884
Preferred term LDP-341
Entry term(s) LDP 341
LDP341
PS 341 - Narrower
Concept UI M0446631
Preferred term PS 341
Entry term(s) 341, PS
PS-341
PS341
Velcade - Narrower
Concept UI M0446632
Preferred term Velcade



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