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Descriptor English: Sitagliptin Phosphate
Descriptor Spanish: Fosfato de Sitagliptina
Descriptor fosfato de sitagliptina
Scope note: INHIBIDOR DE LA DIPEPTIDIL-PEPTIDASA IV derivado de la pirazina e HIPOGLUCEMIANTE que aumenta los niveles de las hormonas INCRETINAS: PÉPTIDO 1 SIMILAR AL GLUCAGÓN (GLP-1) y polipéptido insulinotrópico dependiente de glucosa (POLIPÉPTIDO INHIBIDOR GÁSTRICO). Se utiliza en el tratamiento de la DIABETES MELLITUS TIPO 2.
Descriptor Portuguese: Fosfato de Sitagliptina
Descriptor French: Phosphate de sitagliptine
Entry term(s): 0431, MK
4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine
Anhydrous, Sitagliptin Phosphate
Januvia
MK 0431
MK-0431
MK0431
Monohydrate, Sitagliptin Monophosphate
Monohydrate, Sitagliptin Phosphate
Monophosphate Monohydrate, Sitagliptin
Phosphate Anhydrous, Sitagliptin
Phosphate Monohydrate, Sitagliptin
Phosphate, Sitagliptin
Sitagliptin
Sitagliptin Monophosphate Monohydrate
Sitagliptin Phosphate Anhydrous
Sitagliptin Phosphate Monohydrate
Tree number(s): D03.383.129.799.725
D03.383.679.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068900
Scope note: A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Hypoglycemic Agents
Incretins
Dipeptidyl-Peptidase IV Inhibitors
Registry Number: TS63EW8X6F
Public MeSH Note: 2016; SITAGLIPTIN PHOSPHATE was indexed under PYRAZINES and TRIAZOLES 2005-2015
History Note: 2016 (2005)
Related: Linagliptin MeSH
DeCS ID: 55921
Unique ID: D000068900
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/09
Revision Date: 2016/05/31
Sitagliptin Phosphate - Preferred
Concept UI M0498840
Scope note A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
Preferred term Sitagliptin Phosphate
Entry term(s) Monohydrate, Sitagliptin Monophosphate
Monohydrate, Sitagliptin Phosphate
Monophosphate Monohydrate, Sitagliptin
Phosphate Monohydrate, Sitagliptin
Phosphate, Sitagliptin
Sitagliptin Monophosphate Monohydrate
Sitagliptin Phosphate Monohydrate
MK 0431 - Narrower
Concept UI M0480816
Preferred term MK 0431
Entry term(s) 0431, MK
MK-0431
MK0431
Sitagliptin Phosphate Anhydrous - Narrower
Concept UI M0584641
Preferred term Sitagliptin Phosphate Anhydrous
Entry term(s) Anhydrous, Sitagliptin Phosphate
Phosphate Anhydrous, Sitagliptin
Sitagliptin - Narrower
Concept UI M0480815
Preferred term Sitagliptin
Entry term(s) 4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine
Januvia - Narrower
Concept UI M0495062
Preferred term Januvia



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