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Descriptor English: Type VII Secretion Systems
Descriptor Spanish: Sistemas de Secreción Tipo VII
Descriptor sistemas de secreción de tipo VII
Entry term(s) sistema de secreción ESX
sistema de secreción de tipo 7
sistema de secreción de tipo VII
Scope note: Sistemas de secreción de las bacterias que tienen una membrana externa que posee ÁCIDO MICÓLICO tales como las MYCOBACTERIACEAE, Corynebacteriaceae y NOCARDIACEAE. Estos son también conocidos como sistemas de secreción ESX debido a que el primero en ser descubierto participó en la secreción de los principales factores de virulencia EsxA y EsxB. Hay varios subtipos de T7SSs los que incluyen los sistemas de secreción ESX-1, ESX-2, ESX-3, ESX-4 y ESX-5. Los subtipos comparten algunos componentes centrales incluyendo un complejo de canal de formación de ATPasa de la membrana interna, una micosina anclada a la membrana y un segundo canal que se extiende por la membrana exterior que contiene ácido micólico.
Descriptor Portuguese: Sistemas de Secreção Tipo VII
Descriptor French: Systèmes de sécrétion de type VII
Entry term(s): ESX Secretion System
ESX Secretion Systems
Secretion System, ESX
Secretion System, T7SS
Secretion Systems, ESX
Secretion Systems, Type 7
Secretion Systems, Type VII
System, ESX Secretion
System, T7SS Secretion
Systems, ESX Secretion
T7SS Secretion System
Type 7 Secretion System
Type 7 Secretion Systems
Type VII Secretion System
Tree number(s): D05.500.890.500.992
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069377
Scope note: Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Bacterial Secretion Systems (2010-2015)
Public MeSH Note: 2016
History Note: 2016
DeCS ID: 55951
Unique ID: D000069377
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2020/05/27
Type VII Secretion Systems - Preferred
Concept UI M000605596
Scope note Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane.
Preferred term Type VII Secretion Systems
Entry term(s) ESX Secretion System
ESX Secretion Systems
Secretion System, ESX
Secretion System, T7SS
Secretion Systems, ESX
Secretion Systems, Type 7
Secretion Systems, Type VII
System, ESX Secretion
System, T7SS Secretion
Systems, ESX Secretion
T7SS Secretion System
Type 7 Secretion System
Type 7 Secretion Systems
Type VII Secretion System



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