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Descriptor English: Type II Secretion Systems
Descriptor Spanish: Sistemas de Secreción Tipo II
Descriptor sistemas de secreción de tipo II
Scope note: Sistemas de secreción de las bacterias Gram-negativas que realizan la secreción de proteínas plegadas. Las proteínas plegadas T2SSs secretadas desde el ESPACIO PERIPLASMÁTICO que se han exportado allí mediante la TRANSLOCASA SEC o los SISTEMAS DE SECRECIÓN TAT, o proteínas plegadas secretadas directamente desde el CITOPLASMA. Los T2SSs tienen cuatro subestructuras, una ATPasa, una plataforma de membrana interna, una pseudopilina y secretina, un complejo de membrana externa que es un canal para la secreción. (Esta secretina bacteriana no es la misma que la hormona mamífera también conocida como SECRETINA.)
Descriptor Portuguese: Sistemas de Secreção Tipo II
Descriptor French: Systèmes de sécrétion de type II
Entry term(s): Bacterial Secretion System, Type II
Secretion System, T2SS
System, T2SS Secretion
T2SS Secretion System
Type 2 Secretion System
Type 2 Secretion Systems
Type II Secretion System
Tree number(s): D05.500.890.500.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069178
Scope note: Gram-negative bacterial secretion systems which carry out the secretion of folded proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner membrane platform, a pseudopilin, and secretin, an outer membrane complex which is a channel for secretion. (This bacterial secretin is not the same as the mammalian hormone also named SECRETIN.)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Bacterial Secretion Systems (2010-2015)
Public MeSH Note: 2016
History Note: 2016
DeCS ID: 55946
Unique ID: D000069178
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2015/06/25
Type II Secretion Systems - Preferred
Concept UI M000604919
Scope note Gram-negative bacterial secretion systems which carry out the secretion of folded proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner membrane platform, a pseudopilin, and secretin, an outer membrane complex which is a channel for secretion. (This bacterial secretin is not the same as the mammalian hormone also named SECRETIN.)
Preferred term Type II Secretion Systems
Entry term(s) Bacterial Secretion System, Type II
Secretion System, T2SS
System, T2SS Secretion
T2SS Secretion System
Type 2 Secretion System
Type 2 Secretion Systems
Type II Secretion System



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