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Descriptor English: Type VI Secretion Systems
Descriptor Spanish: Sistemas de Secreción Tipo VI
Descriptor sistemas de secreción de tipo VI
Scope note: Complejos multiproteicos en las BACTERIAS GRAMNEGATIVAS que introducen proteínas efectoras en células eucariotas o procariotas mediante un mecanismo similar a la cola contráctil de los bacteriófagos. Están formados por un tubo que atraviesa la envoltura celular, rodeado por una lámina contráctil y coronado por un complejo de inyección celular en el extremo; una placa basal que ancla el conjunto en la envoltura celular; y una ATPasa involucrada en la contracción de la lámina contráctil y en el desmontaje del complejo.
Descriptor Portuguese: Sistemas de Secreção Tipo VI
Descriptor French: Systèmes de sécrétion de type VI
Entry term(s): Bacterial Secretion System, Type VI
Secretion Systems, T6SS
Systems, T6SS Secretion
T6SS Secretion Systems
Type 6 Secretion System
Type 6 Secretion Systems
Type VI Secretion System
Tree number(s): D05.500.890.500.984
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069376
Scope note: Multiprotein complexes in GRAM NEGATIVE BACTERIA that deliver effector proteins into eukaryotic or prokaryotic cells by a mechanism similar to the contractile tail of bacteriophages. They are composed of a cell envelope-spanning tube which is surrounded by a contractile sheath and tipped by a cell puncturing complex; a base plate structure that anchors the assembly to the cell envelope; and an ATPase involved in the sheath contraction and disassembly of the complex.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Bacterial Secretion Systems (2010-2015)
Public MeSH Note: 2016
History Note: 2016
DeCS ID: 55950
Unique ID: D000069376
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2015/06/25
Type VI Secretion Systems - Preferred
Concept UI M000605577
Scope note Multiprotein complexes in GRAM NEGATIVE BACTERIA that deliver effector proteins into eukaryotic or prokaryotic cells by a mechanism similar to the contractile tail of bacteriophages. They are composed of a cell envelope-spanning tube which is surrounded by a contractile sheath and tipped by a cell puncturing complex; a base plate structure that anchors the assembly to the cell envelope; and an ATPase involved in the sheath contraction and disassembly of the complex.
Preferred term Type VI Secretion Systems
Entry term(s) Bacterial Secretion System, Type VI
Secretion Systems, T6SS
Systems, T6SS Secretion
T6SS Secretion Systems
Type 6 Secretion System
Type 6 Secretion Systems
Type VI Secretion System



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