Search
Descriptor English: Abatacept
Descriptor Spanish: Abatacept
Descriptor abatacept
Scope note: Una proteína de fusión compuesta por un inmunoconjugado del dominio extracelular de CTLA4 y el dominio Fc de la IgG1 humana. Funciona como un bloqueador de coestimulación de linfocitos T que inhibe el TNF-ALFA y previene la activación de los LINFOCITOS T. Se utiliza en el tratamiento de la ARTRITIS REUMATOIDE.
Descriptor Portuguese: Abatacepte
Descriptor French: Abatacept
Entry term(s): BMS 188667
BMS 224818
BMS-188667
BMS-224818
BMS188667
BMS224818
Belatacept
CTLA-4-Ig
CTLA4 Ig Immunoconjugate
CTLA4-Fc
CTLA4-Ig
CTLA4-Ig Immunoconjugate
Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin
Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin
Immunoconjugate, CTLA4-Ig
LEA29Y
Nulojix
Orencia
Tree number(s): D12.776.124.790.651.114.580.225
D12.776.377.715.548.114.580.225
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069594
Scope note: A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunosuppressive Agents
Antirheumatic Agents
Registry Number: 7D0YB67S97
Public MeSH Note: 2016; ABATACEPT was indexed under IMMUNOCONJUGATES 2002-2015
History Note: 2016 (2002)
Related: CTLA-4 Antigen MeSH
DeCS ID: 55984
Unique ID: D000069594
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2017/06/07
Abatacept - Preferred
Concept UI M0442852
Scope note A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Preferred term Abatacept
LEA29Y - Narrower
Concept UI M0498621
Preferred term LEA29Y
BMS224818 - Narrower
Concept UI M0498619
Preferred term BMS224818
Entry term(s) BMS 224818
BMS-224818
Belatacept - Narrower
Concept UI M0498618
Preferred term Belatacept
Orencia - Narrower
Concept UI M0497994
Preferred term Orencia
BMS 188667 - Narrower
Concept UI M0498617
Preferred term BMS 188667
Entry term(s) BMS-188667
BMS188667
CTLA-4-Ig - Narrower
Concept UI M0498620
Preferred term CTLA-4-Ig
Entry term(s) CTLA4 Ig Immunoconjugate
CTLA4-Fc
CTLA4-Ig
CTLA4-Ig Immunoconjugate
Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin
Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin
Immunoconjugate, CTLA4-Ig
Nulojix - Narrower
Concept UI M0568539
Preferred term Nulojix



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey