Descriptor English: | ADAMTS4 Protein | ||||||
Descriptor Spanish: |
Proteína ADAMTS4
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Descriptor Portuguese: | Proteína ADAMTS4 | ||||||
Descriptor French: | Protéine ADAMTS4 | ||||||
Entry term(s): |
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein ADAMTS 4 Protein ADAMTS-4 Protein Aggrecanase 1 Aggrecanase-1 |
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Tree number(s): |
D08.811.277.656.675.374.102.500.844 D09.400.430.500.500.844 D12.776.395.033.500.844 D12.776.860.300.085.844 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071121 | ||||||
Scope note: | An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 3.4.24.82 | ||||||
Public MeSH Note: | 2017; ADAMTS4 PROTEIN was indexed under PROCOLLAGEN N-ENDOPEPTIDASE and ADAM PROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1999-2005 |
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History Note: | 2017 (1999) |
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DeCS ID: | 56488 | ||||||
Unique ID: | D000071121 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2017/01/01 | ||||||
Date of Entry: | 2016/07/06 | ||||||
Revision Date: | 2016/02/26 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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ADAMTS4 Protein
- Preferred
Concept UI |
M000613177 |
Scope note | An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS. |
Preferred term | ADAMTS4 Protein |
Entry term(s) |
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein ADAMTS 4 Protein ADAMTS-4 Protein Aggrecanase 1 Aggrecanase-1 |
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