Search
Descriptor English: ADAMTS4 Protein
Descriptor Spanish: Proteína ADAMTS4
Descriptor proteína ADAMTS4
Entry term(s) agrecanasa-1
proteína ADAM con motivos de trombospondina 4
proteína ADAMTS-4
Scope note: Proteasa ADAMTS similar a la PROTEÍNA ADAMTS5. Contiene un motivo C-terminal único de trombospondina (TS) y escinde los AGRECANOS en el CARTÍLAGO. También puede participar en la destrucción del agrecano en la ARTRITIS.
Descriptor Portuguese: Proteína ADAMTS4
Descriptor French: Protéine ADAMTS4
Entry term(s): A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
ADAMTS 4 Protein
ADAMTS-4 Protein
Aggrecanase 1
Aggrecanase-1
Tree number(s): D08.811.277.656.675.374.102.500.844
D09.400.430.500.500.844
D12.776.395.033.500.844
D12.776.860.300.085.844
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071121
Scope note: An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.24.82
Public MeSH Note: 2017; ADAMTS4 PROTEIN was indexed under PROCOLLAGEN N-ENDOPEPTIDASE and ADAM PROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1999-2005
History Note: 2017 (1999)
DeCS ID: 56488
Unique ID: D000071121
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/06
Revision Date: 2016/02/26
ADAMTS4 Protein - Preferred
Concept UI M000613177
Scope note An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.
Preferred term ADAMTS4 Protein
Entry term(s) A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
ADAMTS 4 Protein
ADAMTS-4 Protein
Aggrecanase 1
Aggrecanase-1



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey