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Descriptor in English: ADAM Proteins
Descriptor in Spanish: Proteínas ADAM
Descriptor in Portuguese: Proteínas ADAM
Descriptor in French: Protéines ADAM
Entry term(s): A Disintegrin and Metalloprotease Proteins
ADAM (A Disintegrin and Metalloprotease) Proteins
Tree number(s): D08.811.277.656.675.374.102
D09.400.430.500
D12.776.395.033
Scope note: A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2006
DeCS UI: 50583
Descriptor UI: D051722
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2006/07/05
ADAM Proteins - Preferred
Concept UI M0481642
Scope note A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.
Preferred term ADAM Proteins
Entry term(s) A Disintegrin and Metalloprotease Proteins
ADAM (A Disintegrin and Metalloprotease) Proteins



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