| Descriptor English: | Placenta Growth Factor | ||||||
| Descriptor Spanish: |
Factor de Crecimiento Placentario
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| Descriptor Portuguese: | Fator de Crescimento Placentário | ||||||
| Descriptor French: | Facteur de croissance placentaire | ||||||
| Entry term(s): |
Factor, Placenta Growth Growth Factor, Placenta Placenta Growth Factor, PLGF 1 Isoform Placenta Growth Factor, PLGF 2 Isoform Placenta Growth Factor, PLGF 3 Isoform Placenta Growth Factor, PLGF 4 Isoform Placenta Growth Factor, PLGF-1 Isoform Placenta Growth Factor, PLGF-2 Isoform Placenta Growth Factor, PLGF-3 Isoform Placenta Growth Factor, PLGF-4 Isoform |
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| Tree number(s): |
D12.644.276.100.800.100 D12.776.780.551 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000072483 | ||||||
| Scope note: | An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | 144589-93-5 | ||||||
| Public MeSH Note: | 2017; PLACENTA GROWTH FACTOR was indexed under PREGNANCY PROTEINS 1991-2016 |
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| History Note: | 2017 (1991) |
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| DeCS ID: | 56528 | ||||||
| Unique ID: | D000072483 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Placenta Growth Factor
- Preferred
Placenta Growth Factor, PLGF-1 Isoform
- Narrower
Placenta Growth Factor, PLGF-3 Isoform
- Narrower
Placenta Growth Factor, PLGF-4 Isoform
- Broader
Placenta Growth Factor, PLGF-2 Isoform
- Narrower
| Concept UI |
M0193636 |
| Scope note | An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer. |
| Preferred term | Placenta Growth Factor |
| Entry term(s) |
Factor, Placenta Growth Growth Factor, Placenta |
| Concept UI |
M0541086 |
| Preferred term | Placenta Growth Factor, PLGF-1 Isoform |
| Entry term(s) |
Placenta Growth Factor, PLGF 1 Isoform |
| Concept UI |
M0541085 |
| Preferred term | Placenta Growth Factor, PLGF-3 Isoform |
| Entry term(s) |
Placenta Growth Factor, PLGF 3 Isoform |
| Concept UI |
M000619286 |
| Preferred term | Placenta Growth Factor, PLGF-4 Isoform |
| Entry term(s) |
Placenta Growth Factor, PLGF 4 Isoform |
| Concept UI |
M0541087 |
| Preferred term | Placenta Growth Factor, PLGF-2 Isoform |
| Entry term(s) |
Placenta Growth Factor, PLGF 2 Isoform |
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