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Descriptor English: Perilipin-3
Descriptor Spanish: Perilipina-3
Descriptor perilipina 3
Entry term(s) perilipina-3
proteína 1 de unión a los receptores de manosa-6-fosfato
proteína 1 de unión al receptor de manosa-6-fosfato
proteína PLIN3
proteína TIP47
proteína TIP47 de selección de carga
proteína de 47 kDa de unión a MPR
proteína de 47 kDa de unión a los receptores de manosa-6-fosfato
proteína de 47 kDa de unión al receptor de manosa-6-fosfato
proteína de 47 kDa que interacciona con la cola (tail interacting)
proteína de selección de carga TIP47
proteína de unión a MPR de 47 kDa
proteína perilipina 3
proteína placentaria 17
Scope note: Perilipina que se localiza en las GOTAS LIPÍDICAS, el CITOPLASMA, los ENDOSOMAS y la MEMBRANA PLASMÁTICA, especialmente en los MACRÓFAGOS. Funciona como transportador de ácidos grasos libres a las GOTAS LIPÍDICAS para promover su biogénesis y crecimiento. También es necesaria para el transporte del RECEPTOR DE MANOSA-6-FOSFATO desde los ENDOSOMAS a la RED TRANS-GOLGI. Su estructura consta de cuatro haces de hélices que interaccionan con la superficie hidrofóbica de las gotas lipídicas.
Descriptor Portuguese: Perilipina-3
Descriptor French: Périlipine-3
Entry term(s): 47 kDa MPR binding Protein
47 kDa MPR-binding Protein
47 kDa Mannose 6 Phosphate Receptor Binding Protein
47 kDa Mannose 6-Phosphate Receptor-Binding Protein
Cargo Selection Protein TIP47
Mannose 6 Phosphate Receptor Binding Protein 1
Mannose-6-Phosphate Receptor-Binding Protein 1
PLIN3 Protein
Perilipin 3
Perilipin 3 Protein
Placental Protein 17
Protein, PLIN3
Protein, Perilipin 3
Protein, TIP47
TIP47 Protein
Tail Interacting Protein of 47 kDa
Tree number(s): D12.776.157.464.500.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000070796
Scope note: A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; PERILIPIN-3 was indexed under CARRIER PROTIENS 1983-2004; under DNA-BINDING PROTEINS, INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS, and PREGNANCY PROTEINS 1983-2011; and under VESICULAR TRANSPORT PROTEINS 2011-2016 1983-2011
History Note: 2017 (1983)
DeCS ID: 56573
Unique ID: D000070796
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/01/19
Perilipin-3 - Preferred
Concept UI M000612258
Scope note A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
Preferred term Perilipin-3
Entry term(s) 47 kDa MPR binding Protein
47 kDa MPR-binding Protein
47 kDa Mannose 6 Phosphate Receptor Binding Protein
47 kDa Mannose 6-Phosphate Receptor-Binding Protein
Cargo Selection Protein TIP47
Mannose 6 Phosphate Receptor Binding Protein 1
Mannose-6-Phosphate Receptor-Binding Protein 1
PLIN3 Protein
Perilipin 3
Perilipin 3 Protein
Placental Protein 17
Protein, PLIN3
Protein, Perilipin 3
Protein, TIP47
TIP47 Protein
Tail Interacting Protein of 47 kDa



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