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Descriptor English: Perilipin-1
Descriptor Spanish: Perilipina-1
Descriptor perilipina 1
Entry term(s) perilipina
perilipina A
perilipina B
proteína PERI
proteína Plin
proteína perilipina
proteína perilipina A
proteína perilipina B
Scope note: Proteína de las gotas lipídicas expresada principalmente por los ADIPOCITOS del TEJIDO ADIPOSO BLANCO y del TEJIDO ADIPOSO PARDO. Se colocaliza con los MACRÓFAGOS y las CÉLULAS ESPUMOSAS de las lesiones ateroscleróticas y estabiliza las GOTAS LIPÍDICAS inhibiendo la LIPASA SENSIBLE A HORMONAS. También puede proteger a los TRIGLICÉRIDOS de la hidrólisis dentro de la MEMBRANA PLASMÁTICA y modular la actividad de la COLESTEROL ÉSTER HIDROLASA.
Descriptor Portuguese: Perilipina-1
Descriptor French: Périlipine-1
Entry term(s): PERI Protein
Perilipin
Perilipin 1
Perilipin A Protein
Perilipin B Protein
Perilipin Protein
Plin Protein
Protein, PERI
Protein, Perilipin
Protein, Perilipin A
Protein, Perilipin B
Protein, Plin
Tree number(s): D12.776.157.464.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000070778
Scope note: A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017; PERILIPIN-1 was indexed under CARRIER PROTEINS and PHOSPHOPROTEINS 1991-2016.
History Note: 2017 (1991)
DeCS ID: 56571
Unique ID: D000070778
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/01/15
Perilipin-1 - Preferred
Concept UI M0188823
Scope note A lipid droplet protein that is expressed primarily by ADIPOCYTES of WHITE ADIPOSE TISSUE and BROWN ADIPOSE TISSUE. It co-localizes with MACROPHAGES and FOAM CELLS of artherosclerotic lesions and stabilizes LIPID DROPLETS by inhibiting HORMONE SENSITIVE LIPASE. It may also protect TRIGLYCERIDES against hydrolysis within the PLASMA MEMBRANE and modulate CHOLESTEROL ESTER HYDROLASE activity.
Preferred term Perilipin-1
Entry term(s) PERI Protein
Perilipin
Perilipin 1
Perilipin A Protein
Perilipin B Protein
Perilipin Protein
Plin Protein
Protein, PERI
Protein, Perilipin
Protein, Perilipin A
Protein, Perilipin B
Protein, Plin



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