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Descriptor English: Perilipin-4
Descriptor Spanish: Perilipina-4
Descriptor perilipina 4
Entry term(s) perilipina-4
proteína Plin4
proteína S3-12
proteína perilipina 4
Scope note: Perilipina que se caracteriza por una extensa región de repeticiones de 11 aminoácidos, que forma 5 hélices alfa adyacentes. Se expresa principalmente en el TEJIDO ADIPOSO BLANCO y en los ADIPOCITOS en diferenciación, así como en el músculo esquelético y en el corazón. Es soluble en el citoplasma pero se relocaliza en la superficie de las GOTAS LIPÍDICAS en condiciones de alta concentración de lípidos.
Descriptor Portuguese: Perilipina-4
Descriptor French: Périlipine-4
Entry term(s): Perilipin 4
Perilipin 4 Protein
Plin4 Protein
S3-12 Protein
Tree number(s): D12.776.157.464.500.906
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071229
Scope note: A perilipin protein characterized by an extensive 11-mer repeat region, which forms five adjacent alpha-helices. It is expressed primarily in WHITE ADIPOSE TISSUE and differentiating ADIPOCYTES, as well as skeletal muscle and heart. It is soluble in the cytoplasm but re-localizes to the surface of LIPID DROPLETS under high lipid conditions.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Carrier Proteins (2004-2016)
Membrane Proteins (2004-2016)
Phosphoproteins (2004-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56574
Unique ID: D000071229
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/03/01
Perilipin-4 - Preferred
Concept UI M000613718
Scope note A perilipin protein characterized by an extensive 11-mer repeat region, which forms five adjacent alpha-helices. It is expressed primarily in WHITE ADIPOSE TISSUE and differentiating ADIPOCYTES, as well as skeletal muscle and heart. It is soluble in the cytoplasm but re-localizes to the surface of LIPID DROPLETS under high lipid conditions.
Preferred term Perilipin-4
Entry term(s) Perilipin 4
Perilipin 4 Protein
Plin4 Protein
S3-12 Protein



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