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Descriptor English: Receptor, Notch3
Descriptor Spanish: Receptor Notch3
Descriptor receptor Notch3
Entry term(s) proteína 3 homóloga al locus Notch neurogénico
proteína Notch-3
proteína Notch3
receptor Notch 3
receptor Notch-3
Scope note: Receptor Notch caracterizado por un gran dominio extracelular que contiene 34 repeticiones similares al FACTOR DE CRECIMIENTO EPIDÉRMICO. Interviene en la regulación de la DIFERENCIACIÓN CELULAR, la APOPTOSIS y la PROLIFERACIÓN CELULAR. Las mutaciones en las repeticiones EGF de Notch-3 se asocian a CADASIL.
Descriptor Portuguese: Receptor Notch3
Descriptor French: Récepteur Notch3
Entry term(s): Neurogenic Locus Notch Homolog Protein 3
Notch 3 Protein
Notch 3 Receptor
Notch-3 Protein
Notch-3 Receptor
Notch3 Protein
Notch3 Receptor
Tree number(s): D12.776.543.750.725.875
D12.776.930.770.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071656
Scope note: A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Notch (2006-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56646
Unique ID: D000071656
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15
Receptor, Notch3 - Preferred
Concept UI M000615274
Scope note A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
Preferred term Receptor, Notch3
Entry term(s) Neurogenic Locus Notch Homolog Protein 3
Notch 3 Protein
Notch 3 Receptor
Notch-3 Protein
Notch-3 Receptor
Notch3 Protein
Notch3 Receptor



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