Search
Descriptor English: C2 Domains
Descriptor Spanish: Dominios C2
Descriptor dominios C2
Entry term(s) dominio C2
dominio tipo tensina C2
Scope note: Módulos de proteínas que funcionan en las dianas proteicas de las MEMBRANAS CELULARES. Están formados por un sándwich beta antiparalelo de ocho cadenas, compuesto por un par de láminas beta de cuatro cadenas. La unidad estructural forma un bolsillo en el lado de la membrana de la proteína que interactúa, y coordina la unión de dos a tres iones de calcio; sin embargo, no todos los dominios C2 se unen al calcio. La PROTEÍNA QUINASA C y la FOSFOHIDROLASA PTEN constituyen ejemplos de proteínas con dominios C2.
Descriptor Portuguese: Domínios C2
Descriptor French: Domaines C2
Entry term(s): C2 Domain
C2 Tensin type Domain
C2 Tensin-type Domain
C2 Tensin-type Domains
Domain, C2
Domain, C2 Tensin-type
Domains, C2
Domains, C2 Tensin-type
Tensin-type Domain, C2
Tensin-type Domains, C2
Tree number(s): G02.111.570.820.709.275.750.125
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000070538
Scope note: Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Amino Acid Sequence (1990-2016)
Protein Binding (1990-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56737
Unique ID: D000070538
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09
C2 Domains - Preferred
Concept UI M000610798
Scope note Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.
Preferred term C2 Domains
Entry term(s) C2 Domain
Domain, C2
Domains, C2
C2 Tensin-type Domain - Narrower
Concept UI M000610821
Preferred term C2 Tensin-type Domain
Entry term(s) C2 Tensin type Domain
C2 Tensin-type Domains
Domain, C2 Tensin-type
Domains, C2 Tensin-type
Tensin-type Domain, C2
Tensin-type Domains, C2



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey