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Descriptor English: HMG-Box Domains
Descriptor Spanish: Dominios HMG-Box
Descriptor dominios HMG-box
Entry term(s) dominios HMGB
dominios caja HMG
Scope note: Dominios de unión al ADN presentes en las proteínas de la superfamilia HMGB (o HMG-Box) que incluyen las PROTEÍNAS HMGB arquetípicas, algunos FACTORES DE TRANSCRIPCIÓN de especificidad de secuencia y otras PROTEÍNAS DE UNIÓN AL ADN. Los dominios constan de 70-80 aminoácidos que forman un pliegue en forma de L a partir de tres segmentos helicoidales alfa. El dominio tiene la capacidad de reconocer y/o inducir estructuras de ADN específicas y consigue la accesibilidad del ADN a otras proteínas implicadas en la transcripción, recombinación o reparación del ADN. (Nótese que no todas las PROTEÍNAS DEL GRUPO DE ALTA MOVILIDAD contienen este dominio.)
Descriptor Portuguese: Domínios HMG-Box
Descriptor French: Domaines à boîtes HMG
Entry term(s): Domain, HMG-1-Box
Domain, HMG-Box
Domains, HMG-1-Box
Domains, HMG-Box
HMG 1 Box Domain
HMG Box Domain
HMG Box Domains
HMG-1-Box Domain
HMG-1-Box Domains
HMG-Box Domain
High Mobility Group Box Domains
High Mobility Group-Box Domains
Tree number(s): G02.111.570.820.709.275.750.235
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D024742
Scope note: DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)
Annotation: HIGH MOBILITY GROUP PROTEINS is also available
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: High Mobility Group Proteins (1991-2001)
Public MeSH Note: 2002
History Note: 2002
DeCS ID: 36343
Unique ID: D024742
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/08/03
Revision Date: 2016/05/31
HMG-Box Domains - Preferred
Concept UI M0371731
Scope note DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)
Preferred term HMG-Box Domains
Entry term(s) Domain, HMG-1-Box
Domain, HMG-Box
Domains, HMG-1-Box
Domains, HMG-Box
HMG 1 Box Domain
HMG Box Domain
HMG Box Domains
HMG-1-Box Domain
HMG-1-Box Domains
HMG-Box Domain
High Mobility Group Box Domains
High Mobility Group-Box Domains



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