DeCS

Descriptor English:

Caspase Activation and Recruitment Domain

Descriptor Spanish:

Dominio de Reclutamiento y Activación de Caspasas

Spanish from Spain

Descriptor	dominio de reclutamiento y activación de caspasas
Entry term(s)	dominio CARD dominio de reclutamiento de caspasas dominios CARD dominios de reclutamiento de caspasas dominios de reclutamiento y activación de caspasas
Scope note:	Módulo de interacción homotípica con proteínas de la superfamilia del dominio de la muerte. Está formado por un haz de seis hélices alfa relacionado en cuanto a secuencia y estructura con el DOMINIO DE MUERTE y el DOMINO EFECTOR DE MUERTE. El dominio de activación e incorporación de caspasa (dominio CARD) se asocia típicamente con otras proteínas que presentan CARD, formando tanto dímeros como trímeros. Los dominios CARD pueden presentarse de forma aislada o en combinación con otros dominios de las proteínas adaptadoras de señalización CARD y de iniciación de CASPASAS que intervienen en la APOPTOSIS.

Descriptor Portuguese:

Domínio de Ativação e Recrutamento de Caspases

Descriptor French:

Domaine d'activation et de recrutement des caspases

Entry term(s):

CARD Domain
CARD Domains
Caspase Activation and Recruitment Domains
Caspase Recruitment Domain
Caspase Recruitment Domains
Recruitment Domain, Caspase
Recruitment Domains, Caspase

Tree number(s):

G02.111.570.820.709.275.750.500.395.250

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071476

Scope note:

A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.

Allowable Qualifiers:

DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Amino Acid Sequence (1997-2016)
Apoptosis Regulatory Proteins (2006-2016)
CARD Signaling Adaptor Proteins (2006-2016)

Public MeSH Note:

2017

History Note:

2017

CARD Signaling Adaptor Proteins MeSH

DeCS ID:

56746

Unique ID:

D000071476

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2017/01/01

Date of Entry:

2016/07/08

Revision Date:

2016/05/09

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

Molecular Structure [G02.111.570]

Molecular Structure

Molecular Conformation [G02.111.570.820]

Molecular Conformation

Protein Conformation [G02.111.570.820.709]

Protein Conformation

Protein Structural Elements [G02.111.570.820.709.275]

Protein Structural Elements

Protein Domains [G02.111.570.820.709.275.750]

Protein Domains

Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]

Protein Interaction Domains and Motifs

Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]

Death Domain Superfamily

Caspase Activation and Recruitment Domain [G02.111.570.820.709.275.750.500.395.250]

Caspase Activation and Recruitment Domain

Death Domain [G02.111.570.820.709.275.750.500.395.500]

Death Domain

Death Effector Domain [G02.111.570.820.709.275.750.500.395.750]

Death Effector Domain

Pyrin Domain [G02.111.570.820.709.275.750.500.395.875]

Pyrin Domain

Caspase Activation and Recruitment Domain - Preferred

Concept UI	M000614836
Scope note	A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.
Preferred term	Caspase Activation and Recruitment Domain
Entry term(s)	CARD Domain CARD Domains Caspase Activation and Recruitment Domains Caspase Recruitment Domain Caspase Recruitment Domains Recruitment Domain, Caspase Recruitment Domains, Caspase

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