DeCS

Descriptor English:

Death Domain

Descriptor Spanish:

Dominio de Muerte

Spanish from Spain

Descriptor	dominio de muerte
Entry term(s)	dominios de la muerte
Scope note:	Dominio conservado de interacción con proteínas perteneciente a la superfamilia del dominio de muerte, que es estructuralmente similar al DOMINIO EFECTOR DE MUERTE y al DOMINIO DE INCORPORACIÓN DE CASPASA. Los dominios de la muerte se unen entre ellos para formar oligómeros y están presentes en los RECEPTORES DE DOMINIOS DE MUERTE, donde son necesarios tanto para señalar la APOPTOSIS como para funciones no relacionadas con la apoptosis.

Descriptor Portuguese:

Domínio de Morte

Descriptor French:

Domaine de mort

Entry term(s):

Death Domains

Tree number(s):

G02.111.570.820.709.275.750.500.395.500

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071459

Scope note:

A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.

Allowable Qualifiers:

DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Amino Acid Sequence (1995-2016)
Receptors, Death Domain (2007-2016)
Receptors, Tumor Necrosis Factor (1995-2016)

Public MeSH Note:

2017

History Note:

2017

DeCS ID:

56747

Unique ID:

D000071459

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2017/01/01

Date of Entry:

2016/07/08

Revision Date:

2016/05/09

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

Molecular Structure [G02.111.570]

Molecular Structure

Molecular Conformation [G02.111.570.820]

Molecular Conformation

Protein Conformation [G02.111.570.820.709]

Protein Conformation

Protein Structural Elements [G02.111.570.820.709.275]

Protein Structural Elements

Protein Domains [G02.111.570.820.709.275.750]

Protein Domains

Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]

Protein Interaction Domains and Motifs

Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]

Death Domain Superfamily

Caspase Activation and Recruitment Domain [G02.111.570.820.709.275.750.500.395.250]

Caspase Activation and Recruitment Domain

Death Domain [G02.111.570.820.709.275.750.500.395.500]

Death Domain

Death Effector Domain [G02.111.570.820.709.275.750.500.395.750]

Death Effector Domain

Pyrin Domain [G02.111.570.820.709.275.750.500.395.875]

Pyrin Domain

Death Domain - Preferred

Concept UI	M000614793
Scope note	A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.
Preferred term	Death Domain
Entry term(s)	Death Domains

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