DeCS

Descriptor English:

Pyrin Domain

Descriptor Spanish:

Dominio Pirina

Spanish from Spain

Descriptor	dominio pyrin
Entry term(s)	dominio DAPIN dominio PAAD dominio PYD
Scope note:	Dominio de interacción con proteínas de la superfamilia de dominios de la muerte. Se caracteriza por un fascículo de seis hélices similar a los que presentan los RECEPTORES DE DOMINIOS DE MUERTE. Los dominios pirina se encuentran en distintas proteínas, en especial en las que intervienen en los INFLAMASOMAS, la AUTOFAGIA y la APOPTOSIS. Forman homodímeros o heterodímeros con los dominios de la muerte para facilitar el ensamblaje de los complejos de señalización.

Descriptor Portuguese:

Domínio Pirina

Descriptor French:

Domaine pyrine

Entry term(s):

DAPIN Domain
DAPIN Domains
PAAD DAPIN PYRIN Domain
PAAD-DAPIN-PYRIN Domain
PAAD-DAPIN-PYRIN Domains
PADD Domain
PADD Domains
PYD Domain
PYD Domains
Pyrin Domains

Tree number(s):

G02.111.570.820.709.275.750.500.395.875

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071196

Scope note:

A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.

Allowable Qualifiers:

DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Cytoskeletal Proteins (2001-2016)
Protein Structure, Tertiary (2001-2016)

Public MeSH Note:

2017

History Note:

2017

Pyrin MeSH

DeCS ID:

56749

Unique ID:

D000071196

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2017/01/01

Date of Entry:

2016/07/08

Revision Date:

2016/05/09

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

Molecular Structure [G02.111.570]

Molecular Structure

Molecular Conformation [G02.111.570.820]

Molecular Conformation

Protein Conformation [G02.111.570.820.709]

Protein Conformation

Protein Structural Elements [G02.111.570.820.709.275]

Protein Structural Elements

Protein Domains [G02.111.570.820.709.275.750]

Protein Domains

Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]

Protein Interaction Domains and Motifs

Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]

Death Domain Superfamily

Caspase Activation and Recruitment Domain [G02.111.570.820.709.275.750.500.395.250]

Caspase Activation and Recruitment Domain

Death Domain [G02.111.570.820.709.275.750.500.395.500]

Death Domain

Death Effector Domain [G02.111.570.820.709.275.750.500.395.750]

Death Effector Domain

Pyrin Domain [G02.111.570.820.709.275.750.500.395.875]

Pyrin Domain

Pyrin Domain - Preferred

Concept UI	M000613569
Scope note	A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.
Preferred term	Pyrin Domain
Entry term(s)	DAPIN Domain DAPIN Domains PAAD DAPIN PYRIN Domain PAAD-DAPIN-PYRIN Domain PAAD-DAPIN-PYRIN Domains PADD Domain PADD Domains PYD Domain PYD Domains Pyrin Domains

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