DeCS

Descriptor English:

Death Effector Domain

Descriptor Spanish:

Dominio Efector de Muerte

Spanish from Spain

Descriptor	dominio efector de muerte
Entry term(s)	dominio DED
Scope note:	Módulo de interacción homotípica con proteínas de la superfamilia del dominio de muerte que se compone de un haz de seis hélices alfa. El dominio efector de la muerte comparte similitudes en la secuencia y estructura con los DOMINIOS DE MUERTE y el DOMINIO DE INCORPORACIÓN DE CASPASA. Está presente en muchas proteínas con funciones fundamentales en la APOPTOSIS.

Descriptor Portuguese:

Domínio Efetor de Morte

Descriptor French:

Domaine effecteur de mort

Entry term(s):

DED Domain
DED Domains
Death Effector Domains

Tree number(s):

G02.111.570.820.709.275.750.500.395.750

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071461

Scope note:

A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.

Allowable Qualifiers:

DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Adaptor Proteins, Signal Transducing (1997-2016)
Amino Acid Sequence (1997-2016)
Death Domain Receptor Signaling Adaptor Proteins (2007-2016)

Public MeSH Note:

2017

History Note:

2017

Death Domain Receptor Signaling Adaptor Proteins MeSH

DeCS ID:

56748

Unique ID:

D000071461

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2017/01/01

Date of Entry:

2016/07/08

Revision Date:

2016/05/09

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

Molecular Structure [G02.111.570]

Molecular Structure

Molecular Conformation [G02.111.570.820]

Molecular Conformation

Protein Conformation [G02.111.570.820.709]

Protein Conformation

Protein Structural Elements [G02.111.570.820.709.275]

Protein Structural Elements

Protein Domains [G02.111.570.820.709.275.750]

Protein Domains

Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]

Protein Interaction Domains and Motifs

Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]

Death Domain Superfamily

Caspase Activation and Recruitment Domain [G02.111.570.820.709.275.750.500.395.250]

Caspase Activation and Recruitment Domain

Death Domain [G02.111.570.820.709.275.750.500.395.500]

Death Domain

Death Effector Domain [G02.111.570.820.709.275.750.500.395.750]

Death Effector Domain

Pyrin Domain [G02.111.570.820.709.275.750.500.395.875]

Pyrin Domain

Death Effector Domain - Preferred

Concept UI	M000614795
Scope note	A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.
Preferred term	Death Effector Domain
Entry term(s)	DED Domain DED Domains Death Effector Domains

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