| Descriptor English: | Aldo-Keto Reductase Family 1 Member C2 | ||||||
| Descriptor Spanish: |
Miembro C2 de la Familia 1 de las Aldo-Ceto Reductasas
| ||||||
| Descriptor Portuguese: | Membro C2 da Família 1 de alfa-Ceto Redutase | ||||||
| Descriptor French: | Aldo-keto reductase family 1 member C2 | ||||||
| Entry term(s): |
AKR1C2 Protein Aldo Keto Reductase Family 1 Member C2 Dihydrodiol Dehydrogenase 2 Dihydrodiol Dehydrogenase Bile Acid Binding Protein Dihydrodiol Dehydrogenase-Bile Acid Binding Protein |
||||||
| Tree number(s): |
D08.811.682.047.150.700.156.750 D08.811.682.047.820.284.875 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074422 | ||||||
| Scope note: | Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8). |
||||||
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
| Registry Number: | EC 1.1.1.357 | ||||||
| Previous Indexing: |
Hydroxysteroid Dehydrogenases (2001-2017) |
||||||
| Public MeSH Note: | 2018 |
||||||
| History Note: | 2018 |
||||||
| DeCS ID: | 57017 | ||||||
| Unique ID: | D000074422 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2018/07/13 |
-
-
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
|
|
Aldo-Keto Reductase Family 1 Member C2
- Preferred
| Concept UI |
M000626529 |
| Scope note | Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8). |
| Preferred term | Aldo-Keto Reductase Family 1 Member C2 |
| Entry term(s) |
AKR1C2 Protein Aldo Keto Reductase Family 1 Member C2 Dihydrodiol Dehydrogenase 2 Dihydrodiol Dehydrogenase Bile Acid Binding Protein Dihydrodiol Dehydrogenase-Bile Acid Binding Protein |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
