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Descriptor English: Deleted in Azoospermia 1 Protein
Descriptor Spanish: Proteína 1 Delecionada en la Azoospermia
Descriptor proteína 1 delecionada en la azoospermia
Entry term(s) proteína DAZ-1
proteína DAZ1
Scope note: Proteína con motivo de reconocimiento del ARN esencial para la ESPERMATOGÉNESIS. Promueve la entrada en MEIOSIS de las CÉLULAS GERMINALES masculinas, posiblemente mediante la regulación de la traducción de los ARNm. La proteína DAZ1 se presenta en un grupo de genes similares del CROMOSOMA Y proclive a las deleciones y duplicaciones genéticas. Las deleciones de estos genes, incluido el DAZ1, se asocian a AZOOSPERMIA y OLIGOSPERMIA.
Descriptor Portuguese: Proteína 1 Suprimida em Azoospermia
Descriptor French: Protéine du gène deleted in azoospermia 1
Entry term(s): DAZ 1 Protein
DAZ-1 Protein
DAZ1 Protein
SPGY Protein
Tree number(s): D12.776.157.725.813.375
D12.776.664.962.813.375
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075364
Scope note: An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: RNA-Binding Proteins (1995-2017)
Public MeSH Note: 2018
History Note: 2018
Related: RNA Recognition Motif MeSH
DeCS ID: 57101
Unique ID: D000075364
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/22
Deleted in Azoospermia 1 Protein - Preferred
Concept UI M000630239
Scope note An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.
Preferred term Deleted in Azoospermia 1 Protein
Entry term(s) DAZ 1 Protein
DAZ-1 Protein
DAZ1 Protein
SPGY Protein



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