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Descriptor English: Ticagrelor
Descriptor Spanish: Ticagrelor
Descriptor ticagrelor
Entry term(s) 3-(7-((2-(3,4-difluorofenil)ciclopropil)amino)-5-(propiltio)-3H-(1-3)-triazolo(4,5-d)pirimidin-3-il)-5-(2-hidroxietoxi)ciclopentano-1,2-diol
AZD 6140
AZD-6140
AZD6140
Brilinta
Brilique
Scope note: Análogo del trifosfato de adenosina y antagonista reversible del RECEPTOR PURINÉRGICO P2Y12 que inhibe la AGREGACIÓN PLAQUETARIA mediada por el ADP. Se usa para la prevención de la TROMBOEMBOLIA en pacientes con SÍNDROME CORONARIO AGUDO o con antecedentes de INFARTO DE MIOCARDIO.
Descriptor Portuguese: Ticagrelor
Descriptor French: Ticagrélor
Entry term(s): 3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-(1-3)-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
AZD 6140
AZD-6140
AZD6140
Brilinta
Brilique
Tree number(s): D03.633.100.759.590.138.806
D13.570.583.138.806
D13.570.800.096.815
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077486
Scope note: An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Platelet Aggregation Inhibitors
Purinergic P2Y Receptor Antagonists
Registry Number: GLH0314RVC
CAS Type 1 Name: 1,2-cyclopentanediol, 3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-1,2,3-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-
Public MeSH Note: 2019; TICAGRELOR was indexed under ADENOSINE/analogs&derivatives 2005-2018
History Note: 2019 (2005)
DeCS ID: 57659
Unique ID: D000077486
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19
Ticagrelor - Preferred
Concept UI M0513890
Scope note An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.
Preferred term Ticagrelor
Brilique - Narrower
Concept UI M0558040
Preferred term Brilique
AZD 6140 - Narrower
Concept UI M0489199
Preferred term AZD 6140
Entry term(s) AZD-6140
AZD6140
Brilinta - Narrower
Concept UI M0573146
Preferred term Brilinta
3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-(1-3)-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol - Narrower
Concept UI M0561817
Preferred term 3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-(1-3)-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol



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