| Descriptor English: | Ticagrelor | ||||||
| Descriptor Spanish: |
Ticagrelor
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| Descriptor Portuguese: | Ticagrelor | ||||||
| Descriptor French: | Ticagrélor | ||||||
| Entry term(s): |
3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-(1-3)-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol AZD 6140 AZD-6140 AZD6140 Brilinta Brilique |
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| Tree number(s): |
D03.633.100.759.590.138.806 D13.570.583.138.806 D13.570.800.096.815 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000077486 | ||||||
| Scope note: | An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Platelet Aggregation Inhibitors Purinergic P2Y Receptor Antagonists |
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| Registry Number: | GLH0314RVC | ||||||
| CAS Type 1 Name: | 1,2-cyclopentanediol, 3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-1,2,3-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- | ||||||
| Public MeSH Note: | 2019; TICAGRELOR was indexed under ADENOSINE/analogs&derivatives 2005-2018 |
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| History Note: | 2019 (2005) |
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| DeCS ID: | 57659 | ||||||
| Unique ID: | D000077486 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2019/01/01 | ||||||
| Date of Entry: | 2018/07/09 | ||||||
| Revision Date: | 2018/06/19 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Ticagrelor
- Preferred
Brilique
- Narrower
AZD 6140
- Narrower
Brilinta
- Narrower
3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-(1-3)-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- Narrower
| Concept UI |
M0513890 |
| Scope note | An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION. |
| Preferred term | Ticagrelor |
| Concept UI |
M0558040 |
| Preferred term | Brilique |
| Concept UI |
M0489199 |
| Preferred term | AZD 6140 |
| Entry term(s) |
AZD-6140 AZD6140 |
| Concept UI |
M0573146 |
| Preferred term | Brilinta |
| Concept UI |
M0561817 |
| Preferred term | 3-(7-((2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-(1-3)-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol |
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