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Descriptor English: Puromycin
Descriptor Spanish: Puromicina
Descriptor puromicina
Scope note: ADENOSINA cinnamomi que se encuentra en STREPTOMYCES alboniger. Inhibe la sínteis de proteínas al unirse al ARN. Es un agente antineoplásico y antitripanosómico y se utiiliza en investigación como inhibidor de la síntesis proteíca.
Descriptor Portuguese: Puromicina
Descriptor French: Puromycine
Entry term(s): CL 13900
CL-13900
CL13900
P 638
P-638
P638
Puromycin Dihydrochloride
Puromycin Hydrochloride
Stylomycin
Tree number(s): D02.241.223.200.380
D03.633.100.759.590.138.711
D09.408.051.788
D13.570.583.138.711
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011691
Scope note: A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Protein Synthesis Inhibitors
Trypanocidal Agents
Registry Number: 4A6ZS6Q2CL
CAS Type 1 Name: Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)-
Public MeSH Note: 65
History Note: 65(63)
DeCS ID: 23434
Unique ID: D011691
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Puromycin - Preferred
Concept UI M0018173
Scope note A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
Preferred term Puromycin
P-638 - Narrower
Concept UI M0369376
Preferred term P-638
Entry term(s) P 638
P638
Puromycin Hydrochloride - Narrower
Concept UI M0018174
Preferred term Puromycin Hydrochloride
Stylomycin - Narrower
Concept UI M0369374
Preferred term Stylomycin
CL-13900 - Narrower
Concept UI M0369375
Preferred term CL-13900
Entry term(s) CL 13900
CL13900
Puromycin Dihydrochloride - Narrower
Concept UI M0331274
Preferred term Puromycin Dihydrochloride



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