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Descriptor English: Tenecteplase
Descriptor Spanish: Tenecteplasa
Descriptor tenecteplasa
Entry term(s) Metalyse
TNKasa
Scope note: Enzima activadora tisular del plasminógeno que actúa como fibrinolítico; se usa para la disolución de coágulos sanguíneos, como los que se forman en el INFARTO DE MIOCARDIO agudo.
Descriptor Portuguese: Tenecteplase
Descriptor French: Ténectéplase
Entry term(s): Metalyse
TNKase
Tree number(s): D08.811.277.656.300.760.875.500
D08.811.277.656.959.350.875.500
D12.776.124.125.662.768.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077785
Scope note: A tissue plasminogen activator enzyme that acts as a fibrinolytic agent; it is used for the dissolution of blood clots, such as those that occur in acute MYOCARDIAL INFARCTION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Fibrinolytic Agents
Registry Number: WGD229O42W
Public MeSH Note: 2019; TENECTEPLASE was indexed under TISSUE PLASMINOGEN ACTIVATOR 1999-2018
History Note: 2019 (1999)
DeCS ID: 57758
Unique ID: D000077785
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21
Tenecteplase - Preferred
Concept UI M0335155
Scope note A tissue plasminogen activator enzyme that acts as a fibrinolytic agent; it is used for the dissolution of blood clots, such as those that occur in acute MYOCARDIAL INFARCTION.
Preferred term Tenecteplase
Metalyse - Narrower
Concept UI M0476108
Preferred term Metalyse
TNKase - Narrower
Concept UI M0476109
Preferred term TNKase



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