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Descriptor English: Plasminogen Activators
Descriptor Spanish: Activadores Plasminogénicos
Descriptor activadores del plasminógeno
Scope note: Grupo heterogéneo de enzimas proteolíticas que convierten el PLASMINÓGENO en PLASMINA. Se concentran en los lisosomas de la mayoría de las células y en el endotelio vascular, particularmente en los vasos de la microcirculación.
Descriptor Portuguese: Ativadores de Plasminogênio
Descriptor French: Activateurs du plasminogène
Entry term(s): Extrinsic Plasminogen Activators
Plasminogen Activator
Uterine Tissue Plasminogen Activator
Uterine-Tissue Plasminogen Activator
Tree number(s): D08.811.277.656.300.760.635
D08.811.277.656.959.350.635
D12.776.124.125.662
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010960
Scope note: A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.
Annotation: /antag: consider also PLASMINOGEN INACTIVATORS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.-
Previous Indexing: Enzyme Activation (1974-1975)
Peptide Hydrolases (1975)
Plasminogen (1974-1975)
Public MeSH Note: 76
History Note: 76
DeCS ID: 23425
Unique ID: D010960
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1976/01/01
Date of Entry: 1975/07/25
Revision Date: 2009/07/06
Plasminogen Activators - Preferred
Concept UI M0016994
Scope note A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.
Preferred term Plasminogen Activators
Entry term(s) Plasminogen Activator
Uterine-Tissue Plasminogen Activator - Narrower
Concept UI M0016995
Preferred term Uterine-Tissue Plasminogen Activator
Entry term(s) Uterine Tissue Plasminogen Activator
Extrinsic Plasminogen Activators - Narrower
Concept UI M0016993
Preferred term Extrinsic Plasminogen Activators



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