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Descriptor English: Clofarabine
Descriptor Spanish: Clofarabina
Descriptor Portuguese: Clofarabina
Descriptor French: Clofarabine
Entry term(s): 2 Chloro 2' arabino fluoro 2' deoxyadenosine
2 Chloro 2' fluoroarabino 2' deoxyadenosine
2-Chloro-2'-arabino-fluoro-2'-deoxyadenosine
2-Chloro-2'-fluoroarabino-2'-deoxyadenosine
2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arbinofuranosyl)adenine
2-Chloro-9-(2-deoxy-2-fluoroarabinofuranosyl)adenine
9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
Cl-F-ara-A
Clofarex
Clolar
Evoltra
Tree number(s): D03.633.100.759.646.138.309
D13.570.065.195
D13.695.667.138.309
D13.695.827.068.309
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077866
Scope note: An adenine arabinonucleoside derivative that acts as an antineoplastic antimetabolite. It is used in the treatment of ACUTE LYMPHOID LEUKEMIA in pediatric patients who have relapsed.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Registry Number: 762RDY0Y2H
CAS Type 1 Name: 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
Public MeSH Note: 2019; CLOFARABINE was indexed under ADENINE NUCLEOTIDES and ARABINONUCLEOSIDES 1991-2018
History Note: 2019 (1991)
DeCS ID: 57769
Unique ID: D000077866
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2019/04/29
Clofarabine - Preferred
Concept UI M0186928
Scope note An adenine arabinonucleoside derivative that acts as an antineoplastic antimetabolite. It is used in the treatment of ACUTE LYMPHOID LEUKEMIA in pediatric patients who have relapsed.
Preferred term Clofarabine
Entry term(s) 2 Chloro 2' arabino fluoro 2' deoxyadenosine
2 Chloro 2' fluoroarabino 2' deoxyadenosine
2-Chloro-2'-arabino-fluoro-2'-deoxyadenosine
2-Chloro-2'-fluoroarabino-2'-deoxyadenosine
2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arbinofuranosyl)adenine
2-Chloro-9-(2-deoxy-2-fluoroarabinofuranosyl)adenine
9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
Cl-F-ara-A
Clolar - Narrower
Concept UI M0478771
Preferred term Clolar
Evoltra - Narrower
Concept UI M0498461
Preferred term Evoltra
Clofarex - Narrower
Concept UI M0446643
Preferred term Clofarex



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