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Descriptor English: Parthanatos
Descriptor Spanish: Parthanatos
Descriptor partánatos
Scope note: Tipo de muerte celular regulada que se inicia por la hiperactivación de poli(ADP-ribosa)-polimerasa-1 (PARP-1) como consecuencia de DAÑO DEL ADN, ESTRÉS OXIDATIVO, HIPOXIA, HIPOGLUCEMIA o INFLAMACIÓN. Esto causa FRAGMENTACIÓN DEL ADN y condensación de la CROMATINA.
Descriptor Portuguese: Parthanatos
Descriptor French: Parthanatos
Entry term(s): Cell Death, PARP-1-Dependent
Cell Death, PARP-Dependent
PARP 1 Dependent Cell Death
PARP Dependent Cell Death
PARP-1-Dependent Cell Death
PARP-Dependent Cell Death
Tree number(s): G04.146.954.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000079323
Scope note: A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Cell Death (2008-2019)
Public MeSH Note: 2020
History Note: 2020
DeCS ID: 59187
Unique ID: D000079323
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/05/30
Parthanatos - Preferred
Concept UI M000644242
Scope note A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.
Preferred term Parthanatos
Entry term(s) Cell Death, PARP-1-Dependent
Cell Death, PARP-Dependent
PARP 1 Dependent Cell Death
PARP Dependent Cell Death
PARP-1-Dependent Cell Death
PARP-Dependent Cell Death



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