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Descriptor English: Angiotensin-Converting Enzyme 2
Descriptor Spanish: Enzima Convertidora de Angiotensina 2
Descriptor enzima convertidora de la angiotensina 2
Entry term(s) carboxipeptidasa relacionada con la ECA
carboxipeptidasa relacionada con la enzima convertidora de la angiotensina
enzima ECA2
enzima convertidora de la angiotensina II
enzima de conversión de la angiotensina 2
enzima de conversión de la angiotensina II
proteína ECA2
proteína enzima convertidora de la angiotensina 2
Scope note: Glicoproteína transmembrana con un dominio catalítico extracelular que actúa como carboxipeptidasa. Escinde un único residuo carboxiterminal a partir de muy diversos sustratos. La eficiencia catalítica es 400 veces mayor con la ANGIOTENSINA II como sustrato que con la ANGIOTENSINA I. La enzima convertidora de la angiotensina 2 también es un receptor funcional para la GLICOPROTEÍNA DE LAS ESPÍCULAS DE CORONAVIRUS de los CORONAVIRUS SARS-CoV, SARS-CoV2 y HCoV-NL63.
Descriptor Portuguese: Enzima de Conversão de Angiotensina 2
Descriptor French: Angiotensin-converting enzyme 2
Entry term(s): Carboxypeptidase de type ACE
Carboxypeptidase de type enzyme de conversion de l'angiotensine
Enzyme ACE2
Enzyme-2 de conversion de l'angiotensine
Protéine ACE2
Tree number(s): D08.811.277.656.350.245.042
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000085962
Scope note: A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine
Registry Number: EC 3.4.17.23
DeCS ID: 59495
Unique ID: D000085962
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2021/01/01
Date of Entry: 2020/07/07
Revision Date: 2020/06/09
Angiotensin-converting enzyme 2 - Preferred
Concept UI M0370114
Preferred term Angiotensin-converting enzyme 2
Entry term(s) Carboxypeptidase de type ACE
Carboxypeptidase de type enzyme de conversion de l'angiotensine
Enzyme ACE2
Enzyme-2 de conversion de l'angiotensine
Protéine ACE2



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