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Descriptor English: Lysine Carboxypeptidase
Descriptor Spanish: Lisina Carboxipeptidasa
Descriptor Portuguese: Lisina Carboxipeptidase
Descriptor French: Lysine carboxypeptidase
Entry term(s): Anaphylatoxin Inactivator
Bradykininase
Carboxypeptidase N
Carboxypeptidase, Lysine
Inactivator, Anaphylatoxin
Kininase I
Tree number(s): D08.811.277.656.350.245.450
D08.811.277.656.350.555.750
D08.811.277.656.675.555.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001121
Scope note: A metallocarboxypeptidase that removes C-terminal basic amino acid from peptides and proteins, with preference shown for lysine over arginine. It is a plasma zinc enzyme that inactivates bradykinin and anaphylatoxins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.17.3
Previous Indexing: Arginine (1972-1974)
Carboxypeptidases (1972-1974)
Peptides (1972-1974)
Public MeSH Note: 1997; see ARGININE CARBOXYPEPTIDASE 1991-1996, see CARBOXYPEPTIDASES 1975-1990; for KININASE I see CARBOXYPEPTIDASES 1975-1981
History Note: 1997 (1975)
DeCS ID: 1124
Unique ID: D001121
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09
Lysine Carboxypeptidase - Preferred
Concept UI M0001685
Scope note A metallocarboxypeptidase that removes C-terminal basic amino acid from peptides and proteins, with preference shown for lysine over arginine. It is a plasma zinc enzyme that inactivates bradykinin and anaphylatoxins.
Preferred term Lysine Carboxypeptidase
Entry term(s) Anaphylatoxin Inactivator
Bradykininase
Carboxypeptidase N
Carboxypeptidase, Lysine
Inactivator, Anaphylatoxin
Kininase I



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