| Descriptor English: | 3C Viral Proteases | ||||||
| Descriptor Spanish: |
Proteasas Virales 3C
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| Descriptor Portuguese: | Proteases Virais 3C | ||||||
| Descriptor French: | Protéases virales 3C | ||||||
| Entry term(s): |
3C Proteases 3C Proteinases 3C like Viral Proteases 3C-like Viral Proteases 3Cpro Proteinases |
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| Tree number(s): |
D08.811.277.656.262.500.108 D08.811.277.656.979.250 D12.776.964.900.500.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000086042 | ||||||
| Scope note: | A class of cysteine proteases which play an essential role in VIRUS REPLICATION. They cleave precursor viral POLYPROTEINS to produce functional proteins and enzymes. In addition, they cleave certain host cell proteins such as EUKARYOTIC INITIATION FACTOR-4G. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.4.22.28 | ||||||
| Previous Indexing: |
Peptide Hydrolases (1966-2020) Viral Proteins (1965-2020) |
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| Public MeSH Note: | 2021 |
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| History Note: | 2021 |
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| DeCS ID: | 59499 | ||||||
| Unique ID: | D000086042 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2021/01/01 | ||||||
| Date of Entry: | 2020/07/07 | ||||||
| Revision Date: | 2020/06/22 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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3C Viral Proteases
- Preferred
3C-like Viral Proteases
- Narrower
| Concept UI |
M000731725 |
| Scope note | A class of cysteine proteases which play an essential role in VIRUS REPLICATION. They cleave precursor viral POLYPROTEINS to produce functional proteins and enzymes. In addition, they cleave certain host cell proteins such as EUKARYOTIC INITIATION FACTOR-4G. |
| Preferred term | 3C Viral Proteases |
| Entry term(s) |
3C Proteases 3C Proteinases 3Cpro Proteinases |
| Concept UI |
M000733994 |
| Preferred term | 3C-like Viral Proteases |
| Entry term(s) |
3C like Viral Proteases |
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