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Descriptor English: Glutathione Synthase
Descriptor Spanish: Glutatión Sintasa
Descriptor glutatión sintasa
Entry term(s) glutatión sintetasa
Scope note: Una de las enzimas activas en el ciclo de la gamma-glutamil. Cataliza la síntesis de glutatión a partir de gamma-glutamilcisteína y glicina, en presencia de ATP, con formación de ADP y ortofosfato. EC 6.3.2.3.
Descriptor Portuguese: Glutationa Sintase
Descriptor French: Glutathione synthase
Entry term(s): Glutathione Synthetase
Synthase, Glutathione
Synthetase, Glutathione
Tree number(s): D08.811.464.259.850.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005981
Scope note: One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.3.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.3.2.3
CAS Type 1 Name: gamma-L-Glutamyl-L-cysteine:glycine ligase (ADP-forming)
Previous Indexing: Glutathione (1973-1976)
Peptide Synthetases (1973-1976)
Public MeSH Note: 98; see GLUTATHIONE SYNTHETASE 1991-97; see PEPTIDE SYNTHETASES 1977-90
History Note: 98(77)
DeCS ID: 6125
Unique ID: D005981
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/05/19
Revision Date: 2003/07/09
Glutathione Synthase - Preferred
Concept UI M0009394
Scope note One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.3.
Preferred term Glutathione Synthase
Entry term(s) Glutathione Synthetase
Synthase, Glutathione
Synthetase, Glutathione



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