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Descriptor English: Histidine Ammonia-Lyase
Descriptor Spanish: Histidina Amoníaco-Liasa
Descriptor histidina amoníaco-liasa
Entry term(s) histidasa
Scope note: Enzima que cataliza el primer paso del catabolismo de la histidina, formando ACIDO UROCÁNICO y AMONÍACO a partir de la HISTIDINA. La deficiencia de esta enzima se asocia con unas concentraciones séricas elevadas de histidina. EC 4.3.1.3.
Descriptor Portuguese: Histidina Amônia-Liase
Descriptor French: Histidine ammonia-lyase
Entry term(s): Ammonia-Lyase, Histidine
Deaminase, Histidine
Histidase
Histidinase
Histidine Ammonia Lyase
Histidine Deaminase
Histidine alpha Deaminase
Histidine alpha-Deaminase
alpha-Deaminase, Histidine
Tree number(s): D08.811.520.232.400.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006638
Scope note: An enzyme that catalyzes the first step of histidine catabolism, forming UROCANIC ACID and AMMONIA from HISTIDINE. Deficiency of this enzyme is associated with elevated levels of serum histidine and is called histidinemia (AMINO ACID METABOLISM, INBORN ERRORS).
Annotation: /defic: consider also histidinemia (AMINO ACID METABOLISM, INBORN ERRORS)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 4.3.1.3
CAS Type 1 Name: L-Histidine ammonia-lyase
Public MeSH Note: 98; see HISTIDASE 1991-97, see AMMONIA-LYASES 1973-90
History Note: 98(73)
DeCS ID: 6797
Unique ID: D006638
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2006/07/05
Histidine Ammonia-Lyase - Preferred
Concept UI M0010399
Scope note An enzyme that catalyzes the first step of histidine catabolism, forming UROCANIC ACID and AMMONIA from HISTIDINE. Deficiency of this enzyme is associated with elevated levels of serum histidine and is called histidinemia (AMINO ACID METABOLISM, INBORN ERRORS).
Preferred term Histidine Ammonia-Lyase
Entry term(s) Ammonia-Lyase, Histidine
Deaminase, Histidine
Histidase
Histidinase
Histidine Ammonia Lyase
Histidine Deaminase
Histidine alpha Deaminase
Histidine alpha-Deaminase
alpha-Deaminase, Histidine



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