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Descriptor English: Jaundice, Chronic Idiopathic
Descriptor Spanish: Ictericia Idiopática Crónica
Descriptor ictericia idiopática crónica
Entry term(s) síndrome de Dubin-Johnson
Scope note: Hiperbilirrubinemia benigna, de herencia autosómica recesiva y que se caracteriza por la presencia de un pigmento oscuro en la región centrolobulillar de las células hepáticas. Existe un defecto funcional en la excreción biliar de bilirrubina, colorantes colefílicos, y porfirinas. Las personas afectadas pueden estar asintomáticas o tener vagos síntomas constitucionales o gastrointestinales. Es posible que el hígado se encuentre ligeramente aumentado de volumen, y con la colangiografía oral e intravenosa no se visualiza el tracto biliar.
Descriptor Portuguese: Icterícia Idiopática Crônica
Descriptor French: Ictère chronique idiopathique
Entry term(s): Chronic Idiopathic Jaundice
Chronic Idiopathic Jaundices
Dubin Johnson Syndrome
Dubin-Johnson Syndrome
Hyperbilirubinemia 2
Hyperbilirubinemia 2s
Hyperbilirubinemia II
Hyperbilirubinemia IIs
Idiopathic Jaundice, Chronic
Idiopathic Jaundices, Chronic
Jaundices, Chronic Idiopathic
Syndrome, Dubin-Johnson
Tree number(s): C16.320.565.300.764
C16.614.451.500.250
C18.452.648.300.764
C23.550.291.500.479
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007566
Scope note: A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
DeCS ID: 7735
Unique ID: D007566
NLM Classification: WI 703
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Jaundice, Chronic Idiopathic - Preferred
Concept UI M0011823
Scope note A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.
Preferred term Jaundice, Chronic Idiopathic
Entry term(s) Chronic Idiopathic Jaundice
Chronic Idiopathic Jaundices
Dubin Johnson Syndrome
Dubin-Johnson Syndrome
Hyperbilirubinemia 2
Hyperbilirubinemia 2s
Hyperbilirubinemia II
Hyperbilirubinemia IIs
Idiopathic Jaundice, Chronic
Idiopathic Jaundices, Chronic
Jaundices, Chronic Idiopathic
Syndrome, Dubin-Johnson



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