DeCS

Descriptor English:

Granulomatous Disease, Chronic

Descriptor Spanish:

Enfermedad Granulomatosa Crónica

Spanish from Spain

Descriptor

enfermedad granulomatosa crónica

Scope note:

Defecto de la función de los leucocitos en el que las células ingieren las bacterias pero no las digieren lo que da lugar a infecciones bacterianas recurrentes con formación de granulomas. Cuando la enfermedad granulomatosa crónica es causada por mutaciones del gen CYBB, la afección es hereditaria con un patrón recesivo ligado al cromosoma X. Cuando es debida a mutaciones de los genes CYBA, NCF1, NCF2, o NCF4 se hereda con patrón autosómico recesivo.

Descriptor Portuguese:

Doença Granulomatosa Crônica

Descriptor French:

Granulomatose septique chronique

Entry term(s):

Autosomal Recessive Chronic Granulomatous Disease
Chronic Granulomatous Disease
Chronic Granulomatous Disease, Atypical
Chronic Granulomatous Disease, X Linked
Chronic Granulomatous Disease, X-Linked
Chronic Granulomatous Diseases
Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked
Cytochrome B-Positive Granulomatous Disease, Chronic, X-Linked
Granulomatous Disease, Chronic, X-Linked
Granulomatous Disease, Chronic, X-Linked, Variant
Granulomatous Diseases, Chronic
X Linked Chronic Granulomatous Disease
X-Linked Chronic Granulomatous Disease

Tree number(s):

C15.378.553.774.535
C16.320.322.233
C20.673.774.535
C23.550.291.500.423

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D006105

Scope note:

A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.

Annotation:

also called granulomatous disease of childhood

Allowable Qualifiers:

BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology

Concept UI	M0009615
Scope note	A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
Preferred term	Granulomatous Disease, Chronic
Entry term(s)	Chronic Granulomatous Disease Chronic Granulomatous Diseases Granulomatous Diseases, Chronic

Concept UI	M0584994
Preferred term	Autosomal Recessive Chronic Granulomatous Disease

Concept UI	M0564717
Preferred term	Granulomatous Disease, Chronic, X-Linked
Entry term(s)	Chronic Granulomatous Disease, Atypical Chronic Granulomatous Disease, X Linked Chronic Granulomatous Disease, X-Linked Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked Cytochrome B-Positive Granulomatous Disease, Chronic, X-Linked Granulomatous Disease, Chronic, X-Linked, Variant X Linked Chronic Granulomatous Disease X-Linked Chronic Granulomatous Disease

We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.