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Descriptor English: Ketone Bodies
Descriptor Spanish: Cuerpos Cetónicos
Descriptor cuerpos cetónicos
Entry term(s) cuerpos de acetona
Scope note: Las sustancias ácido beta-hidroxibutírico, ácido acetoacético y acetona, que son producidas por el metabolismo de los ácidos grasos y de los hidratos de carbono en el hígado en una razón de aproximadamente 78:20:2. Se produce acetoacetato a partir del acetil-CoA. La mayor parte es convertida enzimáticamente a ceto-butirato, pero una pequeña cantidad es descarboxilada de modo espontáneo a acetona. Los cuerpos cetónicos pueden ser utilizados como carburante por el tejido muscular y cerebral. En la inanición y en la diabetes mellitus descompesada se producen grandes cantidades de cuerpos cetónicos, con lo que se produce acidosis metabólica y unas elevadas concentracioenes en sangre y orina de los tres cuerpos cetónicos. (Dorland, 28th ed)
Descriptor Portuguese: Corpos Cetônicos
Descriptor French: Corps cétoniques
Entry term(s): Acetone Bodies
Bodies, Acetone
Bodies, Ketone
Tree number(s): D02.522.585
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007657
Scope note: The metabolic substances ACETONE; 3-HYDROXYBUTYRIC ACID; and acetoacetic acid (ACETOACETATES). They are produced in the liver and kidney during FATTY ACIDS oxidation and used as a source of energy by the heart, muscle and brain.
Annotation: ketogenesis is probably KETONE BODIES /biosyn
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Related: Ketosis MeSH
DeCS ID: 7822
Unique ID: D007657
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2010/06/25
Ketone Bodies - Preferred
Concept UI M0011993
Scope note The metabolic substances ACETONE; 3-HYDROXYBUTYRIC ACID; and acetoacetic acid (ACETOACETATES). They are produced in the liver and kidney during FATTY ACIDS oxidation and used as a source of energy by the heart, muscle and brain.
Preferred term Ketone Bodies
Entry term(s) Bodies, Ketone
Acetone Bodies - Narrower
Concept UI M0011992
Preferred term Acetone Bodies
Entry term(s) Bodies, Acetone



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