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Descriptor English: Methadone
Descriptor Spanish: Metadona
Descriptor metadona
Scope note: Opioide sintético que se utiliza como hidrocloruro. Es un analgésico opioide que es principalmente un agonista mu-opioide. Tiene acciones y empleos similalres a los de la MORFINA.Tiene también una acción antidepresiva sobre el centro de la tos y puede administrarse para el control de la tos intratable asociada a cáncer de pulmón terminal. También se utiliza la metadona como parte del tratamiento de dependencia de los opioides, aunque el empleo prolongado de la propia metadona puede dar lugar a dependencia. (Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
Descriptor Portuguese: Metadona
Descriptor French: Méthadone
Entry term(s): Amidone
Biodone
Dolophine
Hydrochloride, Methadone
Metadol
Metasedin
Methaddict
Methadone Hydrochloride
Methadose
Methex
Phenadone
Phymet
Physeptone
Pinadone
Symoron
Tree number(s): D02.522.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008691
Scope note: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
Annotation: for methadone maintenance treatment, coordinate with OPIATE SUBSTITUTION TREATMENT
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Analgesics, Opioid
Antitussive Agents
Narcotics
Registry Number: UC6VBE7V1Z
CAS Type 1 Name: 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-
Related: Opiate Substitution Treatment MeSH
DeCS ID: 8866
Unique ID: D008691
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Methadone - Preferred
Concept UI M0013541
Scope note A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
Preferred term Methadone
Biodone - Narrower
Concept UI M0474179
Preferred term Biodone
Dolophine - Narrower
Concept UI M0013544
Preferred term Dolophine
Metadol - Narrower
Concept UI M0474180
Preferred term Metadol
Metasedin - Narrower
Concept UI M0474181
Preferred term Metasedin
Symoron - Narrower
Concept UI M0474186
Preferred term Symoron
Methadone Hydrochloride - Narrower
Concept UI M0333590
Preferred term Methadone Hydrochloride
Entry term(s) Hydrochloride, Methadone
Methadose - Narrower
Concept UI M0474183
Preferred term Methadose
Methex - Narrower
Concept UI M0474184
Preferred term Methex
Phenadone - Narrower
Concept UI M0013542
Preferred term Phenadone
Physeptone - Narrower
Concept UI M0013543
Preferred term Physeptone
Entry term(s) Phymet
Pinadone - Narrower
Concept UI M0474185
Preferred term Pinadone
Amidone - Narrower
Concept UI M0013545
Preferred term Amidone
Methaddict - Narrower
Concept UI M0474182
Preferred term Methaddict



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