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Descriptor in English: Ligases
Descriptor in Spanish: Ligasas
Descriptor in Portuguese: Ligases
Descriptor in French: Ligases
Entry term(s): Synthetase
Synthetases
Tree number(s): D08.811.464
Scope note: A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Online Note: use LIGASES & CARBOXY-LYASES to search CARBOXYLASES 1966-74
History Note: CARBOXYLASES was see under CARBOXY-LYASES & LIGASES 1964-74, was heading 1963
DeCS UI: 8201
Descriptor UI: D008025
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2006/07/05
Ligases - Preferred
Concept UI M0012509
Scope note A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.
Preferred term Ligases
Entry term(s) Synthetase
Synthetases



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