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Descriptor English: Lipoproteins, VLDL
Descriptor Spanish: Lipoproteínas VLDL
Descriptor lipoproteínas VLDL
Entry term(s) lipoproteína de muy baja densidad
lipoproteínas de muy baja densidad
lipoproteínas prebeta
pre-beta-lipoproteína
prebeta-lipoproteína
Scope note: Clase de lipoproteínas de partículas muy ligeras (0,93-1,006 g/ml) y de gran tamaño (30-80 nm) con una porción central compuesta principalmente de TRIGLICÉRIDOS y de una monocapa superficial de FOSFOLÍPIDOS y de COLESTEROL en las que quedan incluidas las apolipoproteínas B, E y C. Las VLDL facilitan el transporte de triglicéridos fabricados endógenamente a los tejidos extrahepáticos. A medida que se van eliminando los triglicéridos y la Apo C, la VLDL es convertida a LIPOPROTEÍNAS DE DENSIDAD INTERMEDIA, luego a LIPOPROTEÍNAS DE BAJA DENSIDAD de las que el colesterol es liberado a los tejidos extrahepáticos.
Descriptor Portuguese: Lipoproteínas VLDL
Descriptor French: Lipoprotéines VLDL
Entry term(s): Lipoprotein VLDL II
Lipoprotein, Very-Low-Density
Lipoproteins, VLDL I
Lipoproteins, VLDL III
Lipoproteins, VLDL1
Lipoproteins, VLDL2
Lipoproteins, VLDL3
Lipoproteins, Very-Low-Density
Pre beta Lipoprotein
Pre beta Lipoproteins
Pre-beta-Lipoprotein
Pre-beta-Lipoproteins
Prebeta Lipoprotein
Prebeta Lipoproteins
Prebeta-Lipoprotein
Prebeta-Lipoproteins
VLDL Lipoproteins
VLDL1 Lipoproteins
VLDL2 Lipoproteins
VLDL3 Lipoproteins
Very Low Density Lipoprotein
Very Low Density Lipoproteins
Very-Low-Density Lipoprotein
Very-Low-Density Lipoproteins
Tree number(s): D10.532.599
D12.776.521.622
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008079
Scope note: A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Annotation: hypoprebetalipoproteinemia = LIPOPROTEINS, VLDL /blood (IM) + HYPOLIPOPROTEINEMIAS (IM); /defic: consider also HYPOLIPOPROTEINEMIAS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Lipoproteins (1966-1971)
Public MeSH Note: 74; VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1974-95
History Note: 74(72); VERY-LOW-DENSITY LIPOPROTEINS was VERY LOW DENSITY LIPOPROTEINS 1972-95
DeCS ID: 8253
Unique ID: D008079
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Lipoproteins, VLDL - Preferred
Concept UI M0012596
Scope note A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Preferred term Lipoproteins, VLDL
Entry term(s) Lipoprotein, Very-Low-Density
Lipoproteins, Very-Low-Density
Pre beta Lipoprotein
Pre beta Lipoproteins
Pre-beta-Lipoprotein
Pre-beta-Lipoproteins
Prebeta Lipoprotein
Prebeta Lipoproteins
Prebeta-Lipoprotein
Prebeta-Lipoproteins
VLDL Lipoproteins
Very Low Density Lipoprotein
Very Low Density Lipoproteins
Very-Low-Density Lipoprotein
Very-Low-Density Lipoproteins
Lipoproteins, VLDL2 - Narrower
Concept UI M0012595
Scope note Intermediate density and size VLDL particles (40-60 nm).
Preferred term Lipoproteins, VLDL2
Entry term(s) Lipoprotein VLDL II
VLDL2 Lipoproteins
Lipoproteins, VLDL1 - Narrower
Concept UI M0492982
Scope note Low density large VLDL particles (60-100 nm).
Preferred term Lipoproteins, VLDL1
Entry term(s) Lipoproteins, VLDL I
VLDL1 Lipoproteins
Lipoproteins, VLDL3 - Narrower
Concept UI M0492983
Scope note High density small VLDL particles (30-40 nm).
Preferred term Lipoproteins, VLDL3
Entry term(s) Lipoproteins, VLDL III
VLDL3 Lipoproteins



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