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Descriptor English: ATP Binding Cassette Transporter, Subfamily G, Member 8
Descriptor Spanish: Transportador de Casete de Unión a ATP, Subfamilia G, Miembro 8
Descriptor Portuguese: Membro 8 da Subfamília G de Transportadores de Cassetes de Ligação de ATP
Descriptor French: Membre-8 de la sous-famille G des transporteurs à cassette liant l'ATP
Entry term(s): ABCG8 Protein
ATP Binding Cassette Transporter, Sub-Family G, Member 8
Sterolin 2 Protein
Sterolin-2 Protein
Tree number(s): D10.532.160
D12.776.157.530.100.228.875
D12.776.395.550.020.457.875
D12.776.521.212
D12.776.543.550.192.457.875
D12.776.543.585.100.228.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071019
Scope note: ATP-binding cassette transporter, sub-family G protein that functions as a heterodimer with ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G, MEMBER 5 in the selective transport of DIETARY CHOLESTEROL and PHYTOSTEROLS into and export out of ENTEROCYTES. It also functions in selective sterol excretion by the liver into bile.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: ATP-Binding Cassette Transporters (2000-2016)
Lipoproteins (2000-2016)
Public MeSH Note: 2019; see ATP BINDING CASETTE TRANSPORTER, SUB-FAMILY G, MEMBER 8 2017-2018
History Note: 2019 (2017)
DeCS ID: 56527
Unique ID: D000071019
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2018/07/13
ATP Binding Cassette Transporter, Subfamily G, Member 8 - Preferred
Concept UI M000612935
Scope note ATP-binding cassette transporter, sub-family G protein that functions as a heterodimer with ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G, MEMBER 5 in the selective transport of DIETARY CHOLESTEROL and PHYTOSTEROLS into and export out of ENTEROCYTES. It also functions in selective sterol excretion by the liver into bile.
Preferred term ATP Binding Cassette Transporter, Subfamily G, Member 8
Entry term(s) ABCG8 Protein
ATP Binding Cassette Transporter, Sub-Family G, Member 8
Sterolin 2 Protein
Sterolin-2 Protein



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