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Descriptor English: Moxalactam
Descriptor Spanish: Moxalactam
Descriptor moxalactam
Entry term(s) 1-oxacefalosporina
Scope note: Antibiótico betalactámico de amplio espectro de estructura similar a las CEFALOSPORINAS excepto por la sustitución de la parte oxaazabiciclo por la parte tiaazabiciclo de algunas CEFALOSPORINAS. Ha sido propueso especialmente para las meningitis debido a que atraviesa la barrera hematoencefálica, y en infecciones por anaerobios.
Descriptor Portuguese: Moxalactam
Descriptor French: Latamoxef
Entry term(s): 1 Oxacephalosporin
1-Oxacephalosporin
6059 S
6059-S
6059S
Disodium Latamoxef
Disodium Moxalactam
Disodium, Moxalactam
Festamoxin
Lamoxactam
Latamoxef
Latamoxef, Disodium
Lilly 127935
Ly 127935
Ly-127935
Ly127935
Moxalactam Disodium
Moxalactam, Disodium
S 6059
S-6059
S6059
Shiomarin
Tree number(s): D02.065.589.099.625
D02.886.520.575
D03.633.100.300.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009070
Scope note: Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Registry Number: VUF6C936Z3
CAS Type 1 Name: 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((carboxy(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-
Previous Indexing: Antibiotics (1966-1980)
Cefamandole/analogs & derivatives (1978-1983)
Cephalosporins (1966-1974)
Cephamycins (1975-1977)
Lactams (1972-1980)
Public MeSH Note: 84
History Note: 84
DeCS ID: 9263
Unique ID: D009070
NLM Classification: QV 350
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1983/04/04
Revision Date: 2016/05/31
Moxalactam - Preferred
Concept UI M0014142
Scope note Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Preferred term Moxalactam
Entry term(s) Lamoxactam
Latamoxef
6059-S - Narrower
Concept UI M0351098
Preferred term 6059-S
Entry term(s) 6059 S
6059S
S 6059
S-6059
S6059
Shiomarin - Narrower
Concept UI M0014143
Preferred term Shiomarin
Festamoxin - Narrower
Concept UI M0351096
Preferred term Festamoxin
Lilly 127935 - Narrower
Concept UI M0351095
Preferred term Lilly 127935
Entry term(s) Ly 127935
Ly-127935
Ly127935
1-Oxacephalosporin - Narrower
Concept UI M0014144
Preferred term 1-Oxacephalosporin
Entry term(s) 1 Oxacephalosporin
Moxalactam Disodium - Narrower
Concept UI M0351097
Preferred term Moxalactam Disodium
Entry term(s) Disodium Latamoxef
Disodium Moxalactam
Disodium, Moxalactam
Latamoxef, Disodium
Moxalactam, Disodium



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