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Descriptor English: Nalbuphine
Descriptor Spanish: Nalbufina
Descriptor nalbufina
Scope note: Narcótico utilizado para tratar el dolor. Parece ser agonista de los RECEPTORES OPIOIDES KAPPA y antagonista o agonista parcial de los RECEPTORES OPIOIDES MU.
Descriptor Portuguese: Nalbufina
Descriptor French: Nalbuphine
Entry term(s): EN 2234A
EN-2234A
EN2234A
Nalbuphine Hydrochloride
Nalbuphine Serb
Nubain
Tree number(s): D03.132.577.249.606
D03.605.497.639
D03.633.400.686.639
D04.615.723.795.606
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009266
Scope note: A narcotic used as a pain medication. It appears to be an agonist at KAPPA RECEPTORS and an antagonist or partial agonist at MU RECEPTORS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Analgesics, Opioid
Registry Number: L2T84IQI2K
CAS Type 1 Name: Morphinan-3,6,14-triol, 17-(cyclobutylmethyl)-4,5-epoxy-, (5alpha,6alpha)-
Previous Indexing: Morphinans (1966-1971)
Narcotic Antagonists (1966-1971)
Public MeSH Note: 1991; NALBUPHINE was indexed under MORPHINANS 1972-1990
History Note: 1991 (1972)
DeCS ID: 9458
Unique ID: D009266
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/04/10
Nalbuphine - Preferred
Concept UI M0014433
Scope note A narcotic used as a pain medication. It appears to be an agonist at KAPPA RECEPTORS and an antagonist or partial agonist at MU RECEPTORS.
Preferred term Nalbuphine
Nalbuphine Hydrochloride - Narrower
Concept UI M0330056
Preferred term Nalbuphine Hydrochloride
Nalbuphine Serb - Narrower
Concept UI M000638478
Preferred term Nalbuphine Serb
EN-2234A - Narrower
Concept UI M0352953
Preferred term EN-2234A
Entry term(s) EN 2234A
EN2234A
Nubain - Narrower
Concept UI M0014434
Preferred term Nubain



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