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Descriptor English: Neostigmine
Descriptor Spanish: Neostigmina
Descriptor neostigmina
Entry term(s) sinstigmina
Scope note: Inhibidor de la colinesterasa utilizado en el tratamiento de la miastenia gravis y para revertir los efectos de los relajantes musculares como la galamina y la tubocurarina. La neostigmina, a diferencia de la FISOSTIGMINA, no cruza la barrera hematoencefálica.
Descriptor Portuguese: Neostigmina
Descriptor French: Néostigmine
Entry term(s): Bromide, Neostigmine
Methylsulfate, Neostigmine
Neostigmine Bromide
Neostigmine Methylsulfate
Polstigmine
Proserine
Prostigmin
Prostigmine
Prozerin
Synstigmin
Syntostigmine
Tree number(s): D02.092.877.674.666
D02.675.276.602
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009388
Scope note: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Cholinesterase Inhibitors
Parasympathomimetics
Registry Number: 3982TWQ96G
CAS Type 1 Name: Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-
DeCS ID: 9581
Unique ID: D009388
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Neostigmine - Preferred
Concept UI M0014615
Scope note A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
Preferred term Neostigmine
Entry term(s) Proserine
Prozerin
Synstigmin
Polstigmine - Narrower
Concept UI M0014617
Preferred term Polstigmine
Neostigmine Bromide - Narrower
Concept UI M0351163
Preferred term Neostigmine Bromide
Entry term(s) Bromide, Neostigmine
Syntostigmine - Narrower
Concept UI M0014618
Preferred term Syntostigmine
Neostigmine Methylsulfate - Narrower
Concept UI M0014616
Preferred term Neostigmine Methylsulfate
Entry term(s) Methylsulfate, Neostigmine
Prostigmine - Narrower
Concept UI M0014619
Preferred term Prostigmine
Entry term(s) Prostigmin



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