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Descriptor English: Muscarine
Descriptor Spanish: Muscarina
Descriptor muscarina
Scope note: Alcaloide tóxico hallado en la Amanita muscaria (hongo mosca) y otros hongos de la especie Inocybe. Fue la primera sustancia parasimpaticomimética estudiada y causa una profunda activación parasimpática que puede terminar en convulsiones y muerte. El antídoto específico es la atropina.
Descriptor Portuguese: Muscarina
Descriptor French: Muscarine
Tree number(s): D02.092.877.883.777
D02.675.276.580
D03.132.545
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009116
Scope note: A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It is the first parasympathomimetic substance ever studied and causes profound parasympathetic activation that may end in convulsions and death. The specific antidote is atropine.
Annotation: /biosyn if permitted by plant; do not confuse with the dye muscarine
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Parasympathomimetics
Muscarinic Agonists
Registry Number: 7T101UWZ5W
CAS Type 1 Name: 2-Furanmethanaminium, tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, (2S-(2alpha,4beta,5alpha))-
Previous Indexing: Alkaloids (1968-1976)
Ammonium Compounds (1970-1976)
Furans (1972-1976)
Mycotoxins (1975-1976)
Parasympathomimetics (1966-1976)
Online Note: search PARASYMPATHOMIMETICS 1966-68
History Note: 77; was see under PARASYMPATHOMIMETICS 1963-68
DeCS ID: 9307
Unique ID: D009116
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1976/05/19
Revision Date: 2013/07/08
Muscarine - Preferred
Concept UI M0014225
Scope note A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It is the first parasympathomimetic substance ever studied and causes profound parasympathetic activation that may end in convulsions and death. The specific antidote is atropine.
Preferred term Muscarine



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