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Descriptor English: Acetolactate Synthase
Descriptor Spanish: Acetolactato Sintasa
Descriptor acetolactato sintasa
Entry term(s) acetohidroxiácido sintasa
acetohidroxiácido sintasa I
acetohidroxiácido sintasa III
acetohidroxiácido sintetasa
acetohidroxiácido sintetasa I
acetohidroxiácido sintetasa III
acetolactato sintetasa
sintasa del acetohidroxiácido I
sintasa del ácido acetohidroxílico I
sintasa del ácido acetohidroxílico III
ácido acetohidroxílico sintasa III
Scope note: Flavoproteína que cataliza la formación de acetolactato a partir de 2 moléculas de PIRUVATO en la biosíntesis de VALINA y la formación de acetohidroxibutirato, a partir de piruvato y alfa-cetobutirato en la biosíntesis de ISOLEUCINA. Esta enzima se ha clasificado previamente como EC 4.1.3.18.
Descriptor Portuguese: Acetolactato Sintase
Descriptor French: Acetolactate synthase
Entry term(s): Acetohydroxy Acid Synthase
Acetohydroxy Acid Synthetase
Acetohydroxyacid Synthetase I
Acetolactate Synthetase
Acetoxyhydroxyacid Synthase III
Acid Synthase, Acetohydroxy
Acid Synthetase, Acetohydroxy
Synthase III, Acetoxyhydroxyacid
Synthase, Acetohydroxy Acid
Synthase, Acetolactate
Synthetase I, Acetohydroxyacid
Synthetase, Acetohydroxy Acid
Synthetase, Acetolactate
Tree number(s): D08.811.913.200.324
D12.776.331.049
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000095
Scope note: A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the biosynthesis of VALINE and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of ISOLEUCINE. This enzyme was formerly listed as EC 4.1.3.18.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.2.1.6
CAS Type 1 Name: Acetolactate pyruvate-lyase (carboxylating)
Previous Indexing: Ketoacid-Lyases (1972-1974)
Pyruvates (1972-1974)
Public MeSH Note: 91; was see under KETOACID-LYASES 1975-90
History Note: 91(75); was see under KETOACID-LYASES 1975-90
DeCS ID: 100
Unique ID: D000095
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2005/06/30
Acetolactate Synthase - Preferred
Concept UI M0000140
Scope note A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the biosynthesis of VALINE and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of ISOLEUCINE. This enzyme was formerly listed as EC 4.1.3.18.
Preferred term Acetolactate Synthase
Entry term(s) Acetohydroxy Acid Synthase
Acetohydroxy Acid Synthetase
Acetolactate Synthetase
Acid Synthase, Acetohydroxy
Acid Synthetase, Acetohydroxy
Synthase, Acetohydroxy Acid
Synthase, Acetolactate
Synthetase, Acetohydroxy Acid
Synthetase, Acetolactate
Acetoxyhydroxyacid Synthase III - Narrower
Concept UI M0000141
Preferred term Acetoxyhydroxyacid Synthase III
Entry term(s) Synthase III, Acetoxyhydroxyacid
Acetohydroxyacid Synthetase I - Narrower
Concept UI M0000139
Preferred term Acetohydroxyacid Synthetase I
Entry term(s) Synthetase I, Acetohydroxyacid



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