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Descriptor English: Ornithine Decarboxylase
Descriptor Spanish: Ornitina Descarboxilasa
Descriptor ornitina descarboxilasa
Entry term(s) ornitina carboxiliasa
Scope note: Proteína con fosfato de piridoxal, descrita como limitadora de la velocidad en la biosíntesis de las poliaminas. Cataliza la descarboxilación de la ornitina que da lugar a putrescina, que se enlaza a un residuo de propilamina de la S-adenosilmetionina descarboxilada formando espermidina.
Descriptor Portuguese: Ornitina Descarboxilase
Descriptor French: Ornithine decarboxylase
Entry term(s): Carboxy-lyase, Ornithine
Decarboxylase, Ornithine
Ornithine Carboxy lyase
Ornithine Carboxy-lyase
Tree number(s): D08.811.520.224.125.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009955
Scope note: A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of polyamines. It catalyzes the decarboxylation of ornithine to form putrescine, which is then linked to a propylamine moiety of decarboxylated S-adenosylmethionine to form spermidine.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Ornithine Decarboxylase Inhibitors
Registry Number: EC 4.1.1.17
CAS Type 1 Name: L-Ornithine carboxy-lyase
Previous Indexing: Carboxy-Lyases (1972-1974)
Ornithine (1972-1974)
Public MeSH Note: 84; was see under CARBOXY-LYASES 1975-83
History Note: 84(75); was see under CARBOXY-LYASES 1975-83
DeCS ID: 10133
Unique ID: D009955
NLM Classification: QU 139
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1974/11/11
Revision Date: 2014/06/10
Ornithine Decarboxylase - Preferred
Concept UI M0015433
Scope note A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of polyamines. It catalyzes the decarboxylation of ornithine to form putrescine, which is then linked to a propylamine moiety of decarboxylated S-adenosylmethionine to form spermidine.
Preferred term Ornithine Decarboxylase
Entry term(s) Carboxy-lyase, Ornithine
Decarboxylase, Ornithine
Ornithine Carboxy lyase
Ornithine Carboxy-lyase



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