Descriptor English: | Phosphoenolpyruvate Carboxykinase (GTP) | ||||
Descriptor Spanish: |
Fosfoenolpiruvato Carboxiquinasa (GTP)
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Descriptor Portuguese: | Fosfoenolpiruvato Carboxiquinase (GTP) | ||||
Descriptor French: | Phosphoenolpyruvate carboxykinase (GTP) | ||||
Entry term(s): |
Carboxykinase, GTP-Dependent Phosphoenolpyruvate GTP Dependent Phosphoenolpyruvate Carboxykinase GTP-Dependent Phosphoenolpyruvate Carboxykinase Phosphoenolpyruvate Carboxykinase, GTP-Dependent |
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Tree number(s): |
D08.811.520.224.125.550 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D010729 | ||||
Scope note: | An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32. |
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Annotation: | do not confuse with PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP) |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 4.1.1.32 | ||||
CAS Type 1 Name: | GTP:oxaloacetate carboxy-lyase (transphosphorylating) | ||||
Previous Indexing: |
Carboxy-Lyases (1966-1972) |
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Public MeSH Note: | 98; see PHOSPHOENOLPYRUVATE CARBOXYKINASES 1975-97, see PHOSPHOENOLPYRUVATE CARBOXYKINASE 1973-74 |
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History Note: | 98(73) |
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Entry Version: | PEP CARBOXYKINASE GTP |
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DeCS ID: | 10922 | ||||
Unique ID: | D010729 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1974/01/01 | ||||
Date of Entry: | 1999/01/01 | ||||
Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Phosphoenolpyruvate Carboxykinase (GTP)
- Preferred
Concept UI |
M0016662 |
Scope note | An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32. |
Preferred term | Phosphoenolpyruvate Carboxykinase (GTP) |
Entry term(s) |
Carboxykinase, GTP-Dependent Phosphoenolpyruvate GTP Dependent Phosphoenolpyruvate Carboxykinase GTP-Dependent Phosphoenolpyruvate Carboxykinase Phosphoenolpyruvate Carboxykinase, GTP-Dependent |
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