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Descriptor English: Phosphoenolpyruvate Carboxykinase (GTP)
Descriptor Spanish: Fosfoenolpiruvato Carboxiquinasa (GTP)
Descriptor fosfoenolpiruvato carboxicinasa (GTP)
Scope note: Enzima de la clase liasa que cataliza la conversión de GTP y oxalacetato en GDP, fosfoenolpiruvato y anhídrido carbónico. Esta reacción es parte de la gluconeogénesis hepática. La enzima se encuentra en las mitocondrias y en el citosol del hígado de los mamíferos. (Dorland, 27th ed) EC 4.1.1.32.
Descriptor Portuguese: Fosfoenolpiruvato Carboxiquinase (GTP)
Descriptor French: Phosphoenolpyruvate carboxykinase (GTP)
Entry term(s): Carboxykinase, GTP-Dependent Phosphoenolpyruvate
GTP Dependent Phosphoenolpyruvate Carboxykinase
GTP-Dependent Phosphoenolpyruvate Carboxykinase
Phosphoenolpyruvate Carboxykinase, GTP-Dependent
Tree number(s): D08.811.520.224.125.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010729
Scope note: An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.
Annotation: do not confuse with PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 4.1.1.32
CAS Type 1 Name: GTP:oxaloacetate carboxy-lyase (transphosphorylating)
Previous Indexing: Carboxy-Lyases (1966-1972)
Public MeSH Note: 98; see PHOSPHOENOLPYRUVATE CARBOXYKINASES 1975-97, see PHOSPHOENOLPYRUVATE CARBOXYKINASE 1973-74
History Note: 98(73)
Entry Version: PEP CARBOXYKINASE GTP
DeCS ID: 10922
Unique ID: D010729
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2003/07/09
Phosphoenolpyruvate Carboxykinase (GTP) - Preferred
Concept UI M0016662
Scope note An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.
Preferred term Phosphoenolpyruvate Carboxykinase (GTP)
Entry term(s) Carboxykinase, GTP-Dependent Phosphoenolpyruvate
GTP Dependent Phosphoenolpyruvate Carboxykinase
GTP-Dependent Phosphoenolpyruvate Carboxykinase
Phosphoenolpyruvate Carboxykinase, GTP-Dependent



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