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Descriptor English: Retinaldehyde
Descriptor Spanish: Retinaldehído
Descriptor retinaldehído
Entry term(s) 11-cis-retinal
11-trans-retinal
3,7-dimetil-9-(2,6,6-trimetil-1-ciclohexeno-1-il)-2,4,6,8-nonatetraenal
Axeroftal
aldehído de vitamina A
aldehído retinílico
axeroftal
retinal
retinal todo trans
retineno
Scope note: Diterpeno derivado del carotenoide VITAMINA A que actúa como el componente activo del ciclo visual. Es el grupo prostético de la RODOPSINA (es decir, está unido covalentemente a la OPSINA DE LOS BASTONES como 11-cis-retinal). Cuando es estimulada por la luz visible, la rodopsina transforma este isómero cis del retinal en el isómero trans (11-trans-retinal). Esta transformación endereza la curvatura de la molécula de retinal y provoca un cambio en la forma de la rodopsina que desencadena el proceso visual. Una serie de reacciones catalizadas por enzimas que requieren energía convierten el 11-trans-retinal de nuevo en el isómero cis.
Descriptor Portuguese: Retinaldeído
Descriptor French: Rétinal
Entry term(s): 11-cis-Rétinal
Axérophtal
Rétinaldéhyde
Rétinène
Tree number(s): D02.047.850
D02.455.326.271.665.202.495.690
D02.455.426.392.368.367.379.249.700.690
D02.455.849.131.495.690
D02.455.849.291.605
D23.767.261.700.690
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012172
Scope note: A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Registry Number: RR725D715M
CAS Type 1 Name: Retinal
DeCS ID: 12588
Unique ID: D012172
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/06/09
Rétinal - Preferred
Concept UI M0018957
Preferred term Rétinal
Entry term(s) Axérophtal
Rétinaldéhyde
Rétinène
11-cis-Rétinal - Narrower
Concept UI M0018958
Preferred term 11-cis-Rétinal



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