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Descriptor English: Retinaldehyde
Descriptor Spanish: Retinaldehído
Descriptor Portuguese: Retinaldeído
Descriptor French: Rétinal
Entry term(s): 11 cis Retinal
11-cis-Retinal
Aldehyde, Vitamin A
Axerophthal
Retinal
Retinene
Vitamin A Aldehyde
Tree number(s): D02.047.850
D02.455.326.271.665.202.495.690
D02.455.426.392.368.367.379.249.700.690
D02.455.849.131.495.690
D02.455.849.291.605
D23.767.261.700.690
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012172
Scope note: A carotenoid-derived diterpene that is a constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: RR725D715M
CAS Type 1 Name: Retinal
Public MeSH Note: 91; was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
Online Note: search VITAMIN A 1968-74
History Note: 91(75); was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
DeCS ID: 12588
Unique ID: D012172
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/06/09
Retinaldehyde - Preferred
Concept UI M0018957
Scope note A carotenoid-derived diterpene that is a constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
Preferred term Retinaldehyde
Entry term(s) Aldehyde, Vitamin A
Axerophthal
Retinal
Retinene
Vitamin A Aldehyde
11-cis-Retinal - Narrower
Concept UI M0018958
Preferred term 11-cis-Retinal
Entry term(s) 11 cis Retinal



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