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Descriptor English: Staphylococcal Protein A
Descriptor Spanish: Proteína Estafilocócica A
Descriptor proteína estafilocócica A
Entry term(s) proteína A
Scope note: Proteína presente en la pared celular de la mayoría de las cepas de Staphylococcus aureus. La proteína se une de modo selectivo a la región Fc de la INMUNOGLOBULINA G humana normal y derivada del mieloma. Desencadena actividad de anticuerpo y puede producir reacciones de hipersensibilidad por la liberación de histamina; se ha utilizado también como marcador de antígeno de la superficie celular y en la evaluación clínica de la función de los linfocitos B.
Descriptor Portuguese: Proteína Estafilocócica A
Descriptor French: Protéine A staphylococcique
Entry term(s): Protein A
Protein A, Staphylococcal
Tree number(s): D12.776.097.820
D23.050.161.821
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013205
Scope note: A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, Bacterial (1971-1977)
Bacterial Proteins (1966-1977)
Staphylococcus (1966-1975)
Staphylococcus aureus (1976-1977)
Public MeSH Note: 78
History Note: 78
Entry Version: STAPH PROTEIN A
DeCS ID: 13592
Unique ID: D013205
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1977/05/24
Revision Date: 2016/06/28
Staphylococcal Protein A - Preferred
Concept UI M0020425
Scope note A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
Preferred term Staphylococcal Protein A
Entry term(s) Protein A
Protein A, Staphylococcal



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