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Descriptor English: Coagulase
Descriptor Spanish: Coagulasa
Descriptor coagulasa
Entry term(s) estafilocoagulasa
factor aglutinante estafilocócico
Scope note: Enzimas que intervienen en la coagulación del plasma formando un complejo con la PROTROMBINA humana. Las coagulasas son producidas por ciertos STAPHYLOCOCCUS y por YERSINIA PESTIS. Los estafilococos producen dos tipos de coagulasas: la estafilocoagulasa, una coagulasa libre que produce coagulación verdadera del plasma y el factor estafilocócico de agregación, una coagulasa unida a la pared celular que induce la agregación celular en presencia de fibrinógeno.
Descriptor Portuguese: Coagulase
Descriptor French: Coagulase
Entry term(s): Clumping Factor (Staphylococcal)
Clumping Factor, Staphylococcal
Factor, Staphylococcal Clumping
Staphylocoagulase
Staphylococcal Clumping Factor
Staphylococcus aureus clone pSCa2 of Coagulase
Staphylococcus aureus strain 213 of Coagulase
Staphylococcus aureus strain 8325 4 of Coagulase
Staphylococcus aureus strain 8325-4 of Coagulase
Tree number(s): D08.811.277.656.300.174
D12.776.097.181
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003030
Scope note: Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
Annotation: do not routinely add when indexing coagulase negative organisms; index only when discussed
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Coagulants
Public MeSH Note: 66; was see under HYDROLASES 1963-65; STAPHYLOCOAGULASE was see under HYDROLASES 1963-67
Online Note: use HYDROLASES to search STAPHYLOCOAGULASE 1966-67
History Note: 66(64); was see under HYDROLASES 1963-65; STAPHYLOCOAGULASE was see under HYDROLASES 1963-67
DeCS ID: 3058
Unique ID: D003030
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30
Coagulase - Preferred
Concept UI M0004656
Scope note Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
Preferred term Coagulase
Staphylococcus aureus strain 8325-4 of Coagulase - Narrower
Concept UI M0331205
Preferred term Staphylococcus aureus strain 8325-4 of Coagulase
Entry term(s) Staphylococcus aureus strain 8325 4 of Coagulase
Staphylococcus aureus clone pSCa2 of Coagulase - Narrower
Concept UI M0331203
Preferred term Staphylococcus aureus clone pSCa2 of Coagulase
Staphylococcus aureus strain 213 of Coagulase - Narrower
Concept UI M0331204
Preferred term Staphylococcus aureus strain 213 of Coagulase
Staphylocoagulase - Narrower
Concept UI M0004657
Scope note An extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin.
Preferred term Staphylocoagulase
Staphylococcal Clumping Factor - Narrower
Concept UI M0004655
Preferred term Staphylococcal Clumping Factor
Entry term(s) Clumping Factor (Staphylococcal)
Clumping Factor, Staphylococcal
Factor, Staphylococcal Clumping



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